Persistent URL of this record https://hdl.handle.net/1887/92293
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Targeting intraplaque angiogenesis : imaging and therapeutic interventions
While cholesterol-lowering, anti-inflammatory and anti-platelet therapies benefits can increase survival as a primary or secondary prevention, they are not sufficient for plaque rupture prevention. Moreover, the most advance imaging technologies to detect high-risk atherosclerotic patients fail to visualize and explore cellular events in small preclinical models. Therefore, there is a clear need for the development of new therapies and the application of high-resolution imaging modalities.
In the current thesis, we evaluated new possibilities to inhibit and image intraplaque angiogenesis.
- All authors
- Baganha Carreiras, F.
- Supervisor
- Quax, P.H.A.; Delibegovic, M.
- Co-supervisor
- Vries, M.R. de
- Committee
- Hamming, J.F.; Jukema, J.W.; Goumans, M.J.T.H.; Kuiper, J.; Bot, I.
- Qualification
- Doctor (dr.)
- Awarding Institution
- Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
- Date
- 2020-05-28
- ISBN (print)
- 9789463759113