Anti sense and sensibility : renal and skin effects of (antisense) oligonucleotides

Meer, L. van (2017)

Doctoral Thesis

This thesis describes the clinical investigation of a novel treatment strategy for type 2 diabetes mellitus (t2dm) using an antisense oligonucleotide(aon)to inhibit the sglt2 receptor. Furthermore it describes skin effects of oligonucleotides

• Oligonucleotide
• Antisense
• Type 2 diabetes mellitus
• Clinical trial
• Phase2study

• All authors: Meer, L. van
• Supervisor: Cohen, A.F.; Burggraaf, J.
• Co-supervisor: Moerland, M.
• Committee: Buren, M. van; Pijl, H.; Romijn, J.A.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2017-01-19