Persistent URL of this record https://hdl.handle.net/1887/87898
Documents
-
- Download
- Title Pages _Contents
-
open access
-
- Download
- Part I: Chapter 2
-
open access
- Full text at publishers site
-
- Download
- Part I: Chapter 3
-
open access
- Full text at publishers site
-
- Download
- Part I: Chapter 4
-
open access
-
- Download
- Part II: Chapter 5
-
open access
- Full text at publishers site
-
- Download
- Part II: Chapter 6
-
open access
- Full text at publishers site
-
- Download
- Part II: Chapter 7
-
open access
- Full text at publishers site
-
- Download
- Part II: Chapter 8
-
open access
- Full text at publishers site
-
- Download
- Part II: Chapter 9
-
open access
-
- Download
- Part II: Chapter 10
-
open access
-
- Download
- Summary in English
-
open access
-
- Download
- Summary in Dutch
-
open access
-
- Download
- Summary in Greek
-
open access
-
- Download
- Propositions
-
open access
In Collections
This item can be found in the following collections:
Sleep alterations in the course of aging environmental inputs
beneficial or adverse effects in the course of aging provides significant insights that could accelerate, hinder or ameliorate parts of the aging process allowing for a healthier and longer life span.
Chronic consupmtion of high-caloric diet, eventually leading to obesity, alters the sleep homeostasis as well as the sleep architecture denoting a potentially enhanced aging phenotype.
In addition to dietary preferences, light levels particularly at night significantly affect sleep and the sleep electroencephalogram across a wide age span, impacting
the sleep regulatory system as well as the brain integrity.
Factors that induce beneficial effects include exercise and...Show moreMy research projects include the investigation of effects of different environmental factors on sleep and the circadian clock in the course of aging (such as light levels, exercise, diet and pharmacological substances including caffeine and diazepam). Investigating the
beneficial or adverse effects in the course of aging provides significant insights that could accelerate, hinder or ameliorate parts of the aging process allowing for a healthier and longer life span.
Chronic consupmtion of high-caloric diet, eventually leading to obesity, alters the sleep homeostasis as well as the sleep architecture denoting a potentially enhanced aging phenotype.
In addition to dietary preferences, light levels particularly at night significantly affect sleep and the sleep electroencephalogram across a wide age span, impacting
the sleep regulatory system as well as the brain integrity.
Factors that induce beneficial effects include exercise and caffeine intake. Long-term exercise was able to lead to a younger brain phenotype across all ages while caffeine generally ameliorated sleep health.Show less
- All authors
- Panagiotou, M.
- Supervisor
- Meijer, J.H.
- Co-supervisor
- Boer, T. de
- Committee
- Meijer, O.C.; Rohling, J.H.T.; Slagboom, P.E.; Heemst, D. van; IJzerman, A.P.; Landolt, H.P.; Werf, Y.D. van; Vyazovsiy, V.
- Qualification
- Doctor (dr.)
- Awarding Institution
- Faculty of Medicine, Leiden University Medical Center (LUMC) , Leiden University
- Date
- 2020-05-14
- ISBN (print)
- 9789463807920