Leiden University Scholarly Publications

New polymyxin antibiotics for old problems

Next generation lipopeptide antibiotics

2023 ESC Guidelines for the management of endocarditis

Antibiotic Discovery

Discovery of antibiotics and their targets in multidrug-resistant bacteria

Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms

Real-world effects of antibiotic treatment on acute COPD exacerbations in outpatients

Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning

The ecology and evolution of microbial warfare in streptomyces

Recommendations for antibacterial therapy in adults with COVID-19-an evidence based guideline

The vaginal microbiota in the course of bacterial vaginosis treatment

Rational use of antibiotics

Host-directed therapy for intracellular bacterial Infections

Segmental induction heating of orthopaedic metal implants

Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota

Update of treatment algorithms for Clostridium difficile infection

Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces

Discovery of novel antibiotics from actinomycetes by integrated metabolomics & genomics approaches

Metabolomics-guided analysis of isocoumarin production by Streptomyces species MBT76 and biotransformation of flavonoids and phenylpropanoids

Risk-adapted approach for fever and neutropenia in paediatric cancer patients e A national multicentre study

Risk-adapted approach for fever and neutropenia in paediatric cancer patients e A national multicentre study

Prediction of joint algal toxicity of nano-CeO2/nano-TiO2 and florfenicol: Independent action surpasses concentration addition

Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children

Clostridium difficile infection: the role of antibiotics in outbreak control, epidemiology and treatment