When providing oxygen therapy to a preterm infant, targeting SpO2 is essential for avoiding hypoxaemia and/or hyperoxaemia. However, this can be both difficult and challenging for nurses... Show moreWhen providing oxygen therapy to a preterm infant, targeting SpO2 is essential for avoiding hypoxaemia and/or hyperoxaemia. However, this can be both difficult and challenging for nurses working in a neonatal intensive care unit. The general aim of this thesis project was to assess the effect of changes in clinical practice regarding oxygen titration and compliance with respect to targeting SpO2 in preterm infants admitted to our NICU.The stepwise quality improvement project implemented in this thesis project improved compliance with respect to both targeting SpO2 and improving oxygen titration. This led to improved SpO2 distribution and decreases in both hypoxaemia and hyperoxaemia, as well as slight improvements in the handling of ABC events and oxygen titration following ABC. The introduction of training sessions, guidelines, and automated oxygen control increased awareness regarding the consequences of hypoxaemia and hyperoxaemia and led to increased efforts to prevent complications. Show less