Risk stratification in emergency medicine: towards improved age and sex adjusted risk assessment

Candel, B.G.J. (2024)

Doctoral Thesis

The growing number of older patients presenting to Emergency Departments (EDs) requires better risk stratification to guide treatment and disposition
decisions. Therefore, it is essential to understand the effect of age on the associations between physiological variables and outcomes. More importantly, most risk tools are not age or sex adjusted and are not based on a statistical approach. An age and sex adjusted risk tool could improve risk stratification in the ED.
This thesis is divided into three parts and has four aims, regarding ageadjusted interpretation of physiological variables for risk stratification in ED patients, developing a new age- and sex-adjusted risk tool for the hospital, and describing potential bias if risk tools are used for comparing the quality of care among departments.

• Geriatric Emergency Medicine
• Risk stratification
• Emergency Medicine
• Sepsis
• Trauma
• Hypertension
• Geriatrics
• Early Warning Score

• All authors: Candel, B.G.J.
• Supervisor: Jonge, E. de
• Co-supervisor: Groot, B. de
• Committee: Mooijaart, S.P.; Groenewold, R.H.H.; Arbous, S.M.; Brand, C.L. van den; Brabrand, M.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2024-03-14
• ISBN (print): 9789464834086
• Sponsorship: Máxima Medisch Centrum; Leiden Universitair Medisch Centrum; Nederlandse Vereniging voor Spoedeisende Hulp-artsen; Spoedeisende Geneeskunde Onderzoeksfonds