Structural biochemistry of the pentraxins

Noone, D.P. (2024)

Doctoral Thesis

An investigation of the complement activating pentraxin family of proteins using cryoEM and biochemical techniques.

• Complement
• Pentraxins
• C-reactive protein
• CRP
• Long pentraxin 3
• PTX3
• C1q
• Innate immunity
• cryoEM
• cryo-electron microscopy

• All authors: Noone, D.P.
• Supervisor: Koster, A.J.
• Co-supervisor: Sharp, T.H.
• Committee: Roumenina, L.T.; Dijke, P. ten; Trouw, L.A.; Gaboriauld, C.; Geibel, S.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2024-03-12
• ISBN (print): 9789464960310
• Sponsorship: This research was supported by the following grants to Thomas H Sharp: European Research Council Grant 759517; The Netherlands Organization for Scientific Research Grants OCENW.KLEIN.291 and VI.Vidi.193.014