Functional fluorescent materials and migration dynamics of neural progenitor cells

Bossert, N. (2022)

Doctoral Thesis

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells. The first part of the thesis focuses on two different functional nanomaterials (Ag-DNA and polymersomes), whereas the second part explores fluorescent labeling of neural progenitor cells and their cell dynamics within different in vitro systems.

• Polymersomes
• Long-term imaging
• Ag-DNA
• In vivo biosensors
• NPCs
• Neural progenitor cells
• C17.2 cells
• C17.2 cell migration
• C17.2 cell dynamics
• Fluorescent labeling

• All authors: Bossert, N.
• Supervisor: Bouwmeester, D.
• Co-supervisor: Heinrich, D.M.
• Committee: Noelke, G.; Streichan, S.; Aarts, J.; Schmidt, T.; Noort, S.J.T. van
• Qualification: Doctor (dr.)
• Awarding Institution: Leiden Institute of Physics (LION), Faculty of Science, Leiden University
• Date: 2022-01-13
• Title of host publication: Casimir PhD Series
• ISBN (print): 9789085935094
• Name: 2021-46