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Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury
- All authors
- Wijaya, L.S.; Trairatphisan, P.; Gabor, A.; Niemeijer, M.C.; Keet, J.; Alcalà Morera, A.; Snijders, K.E.; Wink, S.; Yang, H.; Schildknecht, S.; Stevens, J.L.; Bouwman, R.J.P.; Kamp, H.; Hengstler, J.; Beltman, J.B.; Leist, M.; Le Dévédec, S.E.; Saez-Rodriguez, J.; Water, B. van de
- Date
- 2021-05-04
- Journal
- Biochemical Pharmacology
- Volume
- 190