Value of endolymphatic hydrops and perilymph signal intensity in suspected Ménière disease

Steekelenburg, J.M. van; Weijnen, A. van; Pont, L.M.H. de; Vijlbrief, O.D.; Bommelje, C.C.; Koopman, J.P.; Verbist, B.M.; Blom, H.M.; Hammer, S.

doi:doi:10.3174/ajnr.A6410

BACKGROUND AND PURPOSE:M?ni?re disease is characterized by endolymphatic hydrops, whereas perilymphatic enhancement on MR imaging has been suggested to be of additional value in diagnosing M?ni?re disease. This study evaluates the presence of endolymphatic hydrops and perilymphatic enhancement in patients with M?ni?re disease and with other vertigo-associated inner ear pathology.MATERIALS AND METHODS:A 3D-FLAIR sequence 4?hours after intravenous gadolinium injection was performed to visualize the endolymph and perilymph in 220 patients suspected of having M?ni?re disease. Patients? ears were retrospectively categorized as having M?ni?re disease (probable or definite) or other vertigo-associated inner ear pathology not attributable to M?ni?re disease. Endolymphatic hydrops was evaluated using a visual classification system, and perilymphatic enhancement was scored both visually and quantitatively.RESULTS:Endolymphatic hydrops was present in 137 (91.9%) of the definite M?ni?re disease...Show moreBACKGROUND AND PURPOSE:M?ni?re disease is characterized by endolymphatic hydrops, whereas perilymphatic enhancement on MR imaging has been suggested to be of additional value in diagnosing M?ni?re disease. This study evaluates the presence of endolymphatic hydrops and perilymphatic enhancement in patients with M?ni?re disease and with other vertigo-associated inner ear pathology.MATERIALS AND METHODS:A 3D-FLAIR sequence 4?hours after intravenous gadolinium injection was performed to visualize the endolymph and perilymph in 220 patients suspected of having M?ni?re disease. Patients? ears were retrospectively categorized as having M?ni?re disease (probable or definite) or other vertigo-associated inner ear pathology not attributable to M?ni?re disease. Endolymphatic hydrops was evaluated using a visual classification system, and perilymphatic enhancement was scored both visually and quantitatively.RESULTS:Endolymphatic hydrops was present in 137 (91.9%) of the definite M?ni?re disease ears and in 9 (7.0%) of the ears with other vertigo-associated inner ear pathology (PShow less

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Value of endolymphatic hydrops and perilymph signal intensity in suspected Ménière disease