Why do some children easily find their way in social situations and are satisfied with their social lives, while others experience more difficulties? One key component that may explain this is... Show moreWhy do some children easily find their way in social situations and are satisfied with their social lives, while others experience more difficulties? One key component that may explain this is social competence: the ability to fulfill both own and other’s social goals. This thesis focused on individual differences in social competence from childhood to adolescence by examining contextual, developmental and neurobiological influences on aggressive and prosocial responses to social evaluation. Findings showed robust neural processes related to social feedback and subsequent aggression already in middle childhood. Additionally, this thesis revealed that the period between childhood and adolescence is important for the behavioral and neural development of inhibition of aggression following negative, neutral and positive social feedback. Aggression following social feedback decreased towards adolescence, but aggression following positive feedback decreased earlier in childhood than following negative feedback. Moreover, the involvement of the dorsolateral prefrontal cortex, known for its role in executive functioning, decreased over time. Finally, results indicated that the co-occurrence of aggression following rejection and prosocial behavior following observed rejection may possibly protect against externalizing behaviors and promote wellbeing. This thesis highlights the importance of examining the interplay of developmental processes across social contexts to understand mental health outcomes. Show less
Human cooperation is an astonishing phenomenon, as only humans exhibit such immense scale, complexity, and frequency in working together with other people. In this dissertation, I investigate how... Show moreHuman cooperation is an astonishing phenomenon, as only humans exhibit such immense scale, complexity, and frequency in working together with other people. In this dissertation, I investigate how nonverbal communication between two individuals affects cooperative success as well as methodological challenges when examining this topic in laboratory settings. To answer these questions, the dissertation comprises four chapters presenting two theoretical and two methodological studies. In the first two chapters, I demonstrate the beneficial effect of face-to-face interactions on cooperation. I subsequently show that physiological synchrony emerges during social interactions and is positively associated with cooperative success. This finding suggests that physiological synchrony might be an underlying mechanism for the beneficial effect of face contact on cooperation. In the methodological studies, I place the tasks typically used to measure cooperation into the broader context of prosocial behavior. Furthermore, I address the statistical challenges inherent to measuring synchrony between interaction partners. The cardinal point of this dissertation is that interpersonal processes that we are not aware of play a fundamental role in how we behave towards other people. Addressing methodological challenges that come along with studying dyadic interactions will greatly advance our understanding of social phenomena that make us human so unique. Show less
Meulen, M. van der; Wierenga, L.M.; Achterberg, M.; Drenth, N.; IJzendoorn, M.H. van; Crone, E.A. 2020
Prosocial behavior and empathy are important aspects of developing social relations in childhood. Prior studies showed protracted structural development of social brain regions associated with... Show moreProsocial behavior and empathy are important aspects of developing social relations in childhood. Prior studies showed protracted structural development of social brain regions associated with prosocial behavior. However, it remains unknown how structure of the social brain is influenced by genetic or environmental factors, and whether overlapping heritability factors explain covariance in structure of the social brain and behavior. The current study examined this hypothesis in a twin sample (aged 7-9-year; N = 512). Bilateral measures of surface area and cortical thickness of the medial prefrontal cortex (mPFC), temporo-parietal junction (TPJ), posterior superior temporal sulcus (pSTS), and precuneus were analyzed. Results showed genetic contributions to surface area and cortical thickness for all brain regions. We found additional shared environmental influences for TPJ, suggesting that this region might be relatively more sensitive to social experiences. Genetic factors also influenced parent-reported prosocial behavior (A = 45%) and empathy (A = 59%). We provided initial evidence that the precuneus shares genetically determined variance with empathy, suggesting a possible small genetic overlap (9%) in brain structure and empathy. These findings show that structure of the social brain and empathy are driven by a combination of genetic and environmental factors, with some factors overlapping for brain structure and behavior. Show less
Humans have a strong need for social connections, which provide social security and a feeling of social acceptance. Across adolescence, peers emerge as important social interaction partners to... Show moreHumans have a strong need for social connections, which provide social security and a feeling of social acceptance. Across adolescence, peers emerge as important social interaction partners to fulfill the need for social connections. In her dissertation, Elisabeth Schreuders highlights adolescence as a sensitive period for pursuing personal goals and social development through interactions with different familiar peers, particularly friends.Neural reward-related processes and neural processes underlying prosocial behavior were examined using longitudinal and ecologically valid research designs. The findings show involvement of changes in ventral striatum reward sensitivity from early to mid-adolescence in the motivation to pursue personally valued goals, including stable friendships. It was furthermore found that adults who to a lesser extent adhered to the social norm of behaving in a prosocial manner toward friends yielded greater activity in the supplementary motor area and anterior insula. Additionally, exploratory analyses showed that mid-adolescents with greater social competence yielded greater activity in several brain areas implicated in prosocial decision-making involving friends, including the putamen and superior parietal lobule. Together, these findings highlight adolescence as a sensitive period for self and social development, in which social motivations are reflected in interactions with different types of peers. Show less
Meulen, M. van der; Steinbeis, N.A.J.; Achterberg, M.; IJzendoorn, M.H. van; Crone, E.A.M. 2018
Experiencing and observing social exclusion and inclusion, as well as prosocial behavior, are important aspects of social relationships in childhood. However, it is currently unknown to what extent... Show moreExperiencing and observing social exclusion and inclusion, as well as prosocial behavior, are important aspects of social relationships in childhood. However, it is currently unknown to what extent these processes and their neural correlates differ in heritability. We investigated influences of genetics and environment on experiencing social exclusion and compensating for social exclusion of others with the Prosocial Cyberball Game using fMRI in a twin sample (aged 7–9; N = 500). Neuroimaging analyses (N = 283) revealed that experiencing possible self-exclusion resulted in activity in inferior frontal gyrus and medial prefrontal cortex, which was influenced by genetics and unique environment. Experiencing self-inclusion was associated with activity in anterior cingulate cortex, insula and striatum, but this was not significantly explained by genetics or shared environment. We found that children show prosocial compensating behavior when observing social exclusion. Prosocial compensating behavior was associated with activity in posterior cingulate cortex/precuneus, and showed unique environmental effects or measurement error at both behavioral and neural level. Together, these findings show that in children neural activation for experiencing possible self-exclusion and self-inclusion, and for displaying prosocial compensating behavior, is accounted for by unique environmental factors and measurement error, with a small genetic effect on possible self-exclusion. Show less
Schreuders, E.; Klapwijk, E.T.; Will, G.J.; Güroğlu, B. 2018
Although the majority of our social interactions are with people we know, few studies have investigated the neural correlates of sharing valuable resources with familiar others. Using an... Show moreAlthough the majority of our social interactions are with people we know, few studies have investigated the neural correlates of sharing valuable resources with familiar others. Using an ecologically valid research paradigm, this functional magnetic resonance imaging study examined the neural correlates of prosocial and selfish behavior in interactions with real-life friends and disliked peers in young adults. Participants (N = 27) distributed coins between themselves and another person, where they could make selfish choices that maximized their own gains or prosocial choices that maximized outcomes of the other. Participants were more prosocial toward friends and more selfish toward disliked peers. Individual prosociality levels toward friends were associated negatively with supplementary motor area and anterior insula activity. Further preliminary analyses showed that prosocial decisions involving friends were associated with heightened activity in the bilateral posterior temporoparietal junction, and selfish decisions involving disliked peers were associated with heightened superior temporal sulcus activity, which are brain regions consistently shown to be involved in mentalizing and perspective taking in prior studies. Further, activation of the putamen was observed during prosocial choices involving friends and selfish choices involving disliked peers. These findings provide insights into the modulation of neural processes that underlie prosocial behavior as a function of a positive or negative relationship with the interaction partner. Show less
To thrive as an individual and within society, children need to master the ability to control their behavior and adapt it to social rules and standards. They also need to acquire the social... Show moreTo thrive as an individual and within society, children need to master the ability to control their behavior and adapt it to social rules and standards. They also need to acquire the social competence to interact and communicate with others. Studies showing the relevance of behavioral control and social competence for children’s future development give rise to the search for factors that are associated with these competencies. These factors can be characteristics of the child, factors within the child’s social environment, and factors within the physical and socioeconomic environment. In the current thesis we aimed to identify some of these factors associated with the development of behavioral control in early childhood, and with prosocial behavior in early to mid-adolescence. We assessed four types of behavioral control: parent-reported effortful control, observed cheating behavior, delay of gratification, and response inhibition. For prosocial behavior, one type was assessed: observed compensating behavior towards an excluded peer. The results show that there is quite some variation in children’s level of behavioral control as well as in adolescents’ level of prosocial behavior and that these levels can be related to child characteristics, factors in their social environment, physical, and socioeconomic environment in a meaningful way. Show less
The aim of this thesis is to highlight social environmental and neural pro-cesses at play during adolescent prosocial development using an integrative approach of multiple levels of social... Show moreThe aim of this thesis is to highlight social environmental and neural pro-cesses at play during adolescent prosocial development using an integrative approach of multiple levels of social functioning and relationships. This approach integrates adolescent peer relations research with prosocial development perspectives using behavioral, sociometric and neuroimaging techniques. The evidence provided by this thesis and previous studies supports a model that highlights interactions between the peer context, individual prosocial functioning and brain development. In this neuro-ecological model of prosocial development, the morphology of social brain regions develops in interaction with social experiences. Positive experiences could be responsible for the motivation that is necessary for the recruitment of regions that support social cognition skills and thereby facilitate prosocial behavior. Show less
Meulen, M. van der; Steinbeis, N.; Achterberg, M.; Bilo, E.; Bulk, B.G. van den; IJendoorn, M.H. van; Crone, E.A. 2017
Young children endorse norms of fairness but rarely act on them. We investigated whether a failure of behavioral control can partially explain why children do not share more generously than they do... Show moreYoung children endorse norms of fairness but rarely act on them. We investigated whether a failure of behavioral control can partially explain why children do not share more generously than they do. We experimentally manipulated behavioral control and observed its effects on sharing in 120 children aged 6–9 years of age. Using a between-participants design, we presented children with stories in which a protagonist either exerted behavioral control in an unrelated context or not. Following this, children engaged in a sharing task. We found that children who had been read a story promoting behavioral control shared more than children who had been read a neutral story. This effect held over two different types of instruction. Perceptions of fairness, on the other hand, were identical across conditions. These findings speak to the importance of behavioral control in prosocial behavior, and specifically sharing, during middle childhood. Show less
Peer influence plays a crucial role in the rise of health-risk behaviors during adolescence. However, there is increasing evidence that peer influence can also lead to positive psychosocial... Show morePeer influence plays a crucial role in the rise of health-risk behaviors during adolescence. However, there is increasing evidence that peer influence can also lead to positive psychosocial outcomes, such as prosocial behavior. The main goal of this thesis was to investigate peer influence on risk-taking and prosocial behavior in adolescence and to unravel its underlying neural processes. Findings showed that effects of peers on risk-taking behavior are dependent on the context. Adolescents take into account both social norms from peer feedback and the uncertainty associated with outcomes in risky decisions. Moreover, peers can both increase and decrease prosocial behavior in typically developing (TD) adolescents and those with autism spectrum disorders (ASD), illustrating that peer influence can also lead to more adaptive outcomes. Finally, we studied the neural processes underlying prosocial peer feedback and results indicate that prosocial peer influence is underlined by the social brain network, regions involved in thinking about the self and others. Eventually, the results of this thesis can contribute to interventions aimed at decreasing risk-taking and promoting prosocial behavior in adolescence, with possibly long lasting effects into adulthood. Show less
Vrijhof, C.I.; Bulk, B.G. van den; Overgaauw, S.; Lelieveld, G.J.; Engels, R.C.M.E.; IJzendoorn, M.H. van 2016
Children and adolescents who are chronically rejected by their peers suffer from widespread impairments in daily life, ranging from poor academic achievement and dropping out of school, to... Show moreChildren and adolescents who are chronically rejected by their peers suffer from widespread impairments in daily life, ranging from poor academic achievement and dropping out of school, to delinquency and the development of mental health problems. To gain a better understanding of the developmental processes that give rise to such impairments, the research described in this dissertation examined the neurocognitive underpinnings of processes that play a role in the emergence and maintenance of peer group rejection and acceptance. The first part of this dissertation focuses on neurocognitive processes underlying reactions to social exclusion. The second part concentrates on the neurocognitive processes involved in sharing valuable resources, based on the widely established finding that frequent displays of prosocial behaviors, such as cooperating, helping, and sharing, are associated with both gaining and maintaining acceptance among peers. The empirical work in this dissertation demonstrates that a developmental cognitive neuroscience approach provides unique insights into the emotional, regulatory, and socio-cognitive processes thought to play a role in the emergence and maintenance of peer group acceptance and rejection. Show less
As infants are fully dependent on their parents, correct perception and interpretation of infant signals is crucial for infant survival. It is therefore not surprising that specific brain circuits... Show moreAs infants are fully dependent on their parents, correct perception and interpretation of infant signals is crucial for infant survival. It is therefore not surprising that specific brain circuits and neuroendocrine processes have evolved to perceive infant signals correctly and to respond adequately. However, parents vary in their ability to respond to their infants in a sensitive way and several factors may be involved in parental sensitive responsiveness. One important factor influencing parenting behavior is the neuropeptide oxytocin. Of all the hormones involved in parenting and other social behaviors, oxytocin has received the most interest, as evidenced by the high number of scientific studies over the past decade (Bos, Panksepp, Bluthé, & Honk, 2012; Van IJzendoorn & Bakermans-Kranenburg, 2012). Many studies suggest that oxytocin is related to sensitive parenting (Bakermans-Kranenburg & Van IJzendoorn, 2008; Feldman, Weller, Zagoory-Sharon, & Levine, 2007), although the exact mechanism underlying this positive association is not entirely clear yet. Another factor that influences parenting behavior is adult state of mind with respect to attachment (Van IJzendoorn, 1995). In the current dissertation, the role of oxytocin and adult attachment in parenting is examined with a series of functional magnetic resonance imaging experiments. Show less
In the present thesis, a homogeneous upper middle class sample of firstborn girls and their mothers were followed from infancy (18 and 24 months) to middle childhood (89 months) using... Show moreIn the present thesis, a homogeneous upper middle class sample of firstborn girls and their mothers were followed from infancy (18 and 24 months) to middle childhood (89 months) using questionnaires and observations. The focus of the study was on three components of moral behavior, i.e. empathy, compliance and prosocial behavoir. The longitudinal development and stability of empathy and compliance from infancy to middle childhood was described, and their relation to prosocial behavior in middle childhood. Empathic concern towards mother increased from 18 to 24 months, but strongly decreased from 24 to 89 months. Empathic concern toward an unfamiliar person decreased from 18 to 89 months. Compliance increased from 18 to 89 months. Only empathy towards mother seems to be fertile ground for donating to charitable organizations like UNICEF. Also, the role of antecedent and concurrent sensitivity and attachment security in prosocial, externalizing, and internalizing behavior in middle childhood was investigated. Results showed that, controlling for concurrent influences, maternal sensitivity and attachment security in infancy predicted prosocial and externalizing behavior Show less
