The photographic surface is the pivotal carrier of information – be it the mediated image or material indications about the object. It is presented here as the entrance into the study of... Show moreThe photographic surface is the pivotal carrier of information – be it the mediated image or material indications about the object. It is presented here as the entrance into the study of photographic materiality that unfolds in a profound scanning of a photograph’s multi-layered dimensionality and of all the interactions that (can) take place in its lifetime – ranging from human to molecular. The chosen case studies are photoworks (hybrid photographic works of art) that are partially overpainted and show (first) signs of degrading photographic material. The different (material) properties of the two interacting media with their distinct surfaces pose challenging questions on a representational, chemical, conservational as well as a theoretical level. The key concern is: How does the photographic surface act in hybrid photoworks as interface between substances and their surrounding space? By panning back and forth between material, technical, and theoretical studies and the case studies – Tacita Dean’s (*1965) Crowhurst II (2007), and two photoworks by Ger van Elk (1941-2014): Dutch Grey (1983/84) and Russian Diplomacy’s (1974) – I follow the methodological path of a multi-angled analysis of photoworks in order to respond to their hybrid nature and to think with their materiality and subject matter. The result is an in-depth theoretical investigation of the photographic surface as interface between substances and spaces within photoworks in particular, and ontologically in any chemically created photograph. It ties together philosophical, esthetical, technical and ethical point of views and therewith creates a deep understanding of photographic materiality at the verge of digital dominance. Show less
BackgroundKetamine and its enantiomers are widely researched and increasingly used to treat mental disorders, especially treatment-resistant depression. The phenomenology of ketamine-induced... Show moreBackgroundKetamine and its enantiomers are widely researched and increasingly used to treat mental disorders, especially treatment-resistant depression. The phenomenology of ketamine-induced experiences and their relation to its psychotherapeutic potential have not yet been systematically investigated.AimsTo describe the phenomenology of patient experiences during oral esketamine treatment for treatment-resistant depression (TRD) and to explore the potential therapeutic relevance of these experiences.MethodsIn-depth interviews were conducted with 17 patients after a 6-week, twice-weekly ‘off label’ generic oral esketamine (0.5–3.0mg/kg) treatment program. Interviews explored participants’ perspectives, expectations, and experiences with oral esketamine treatment. Audio interviews were transcribed and analyzed using an Interpretative Phenomenological Analysis (IPA) framework.ResultsThe effects of ketamine were highly variable, and psychological distress was common in most patients. Key themes included (a) perceptual effects (auditory, visual, proprioceptive), (b) detachment (from body, self, emotions, and the world), (c) stillness and openness, (d) mystical-type effects (transcendence, relativeness, spirituality), and (e) fear and anxiety. Key themes related to post-session reports included (a) feeling hungover and fatigued, and (b) lifting the blanket: neutralizing mood effects.ConclusionPatients reported several esketamine effects with psychotherapeutic potential, such as increased openness, detachment, an interruption of negativity, and mystical-type experiences. These experiences deserve to be explored further to enhance treatment outcomes in patients with TRD. Given the frequency and severity of the perceived distress, we identify a need for additional support in all stages of esketamine treatment. Show less
