Background The analysis of mobile health (mHealth) data has generated innovative insights into improving allergic rhinitis control, but additive information is needed. A cross-sectional real-world... Show moreBackground The analysis of mobile health (mHealth) data has generated innovative insights into improving allergic rhinitis control, but additive information is needed. A cross-sectional real-world observational study was undertaken in 17 European countries during and outside the estimated pollen season. The aim was to collect novel information including the phenotypic characteristics of the users. Methods The Allergy Diary-MASK-air-mobile phone app, freely available via Google Play and App, was used to collect the data of daily visual analogue scales (VASs) for overall allergic symptoms and medication use. Fluticasone Furoate (FF), Mometasone Furoate (MF), Azelastine Fluticasone Proprionate combination (MPAzeFlu) and eight oral H1-antihistamines were studied. Phenotypic characteristics were recorded at entry. The ARIA severity score was derived from entry data. This was an a priori planned analysis. Results 9037 users filled in 70,286 days of VAS in 2016, 2017 and 2018. The ARIA severity score was lower outside than during the pollen season. Severity was similar for all treatment groups during the pollen season, and lower in the MPAzeFlu group outside the pollen season. Days with MPAzeFlu had lower VAS levels and a higher frequency of monotherapy than the other treatments during the season. Outside the season, days with MPAzeFlu also had a higher frequency of monotherapy. The number of reported days was significantly higher with MPAzeFlu during and outside the season than with MF, FF or oral H1-antihistamines. Conclusions This study shows that the overall efficacy of treatments is similar during and outside the pollen season and indicates that medications are similarly effective during the year. Show less
This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses... Show moreThis dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted. The ability to generate new and potentially useful ideas and problem-solving skills as a result of creative thinking is an important driver of human evolution. According to many, creativity is a very valued and sought-after accomplishment for today's society and for the future. In addition, computers, and everything related to them, have become an integral part of society. The ‘computer’ is one of the most important innovations in the history of mankind. Computers have radically changed our lives. It is even hardly conceivable to innovate without ICT. It is therefore logical that ICT-professionals play an extremely prominent role in innovation. This applies in particular to students taking a Bachelor of ICT-course in a Dutch University of Applied Sciences, because they are trained as leading IT-specialists.These phenomena led to two interrelated research questions: (i) ”Is creativity training important for ICT-students at Dutch hogescholen?”; and (ii): “Does creativity training work, as it is integrated in the curriculum of these ICT-students?” Show less
This thesis focused on the evaluation of an eHealth intervention for cognitive stroke rehabilitation and the perspectives of different stakeholders on the uptake of eRehabilitation in general. The... Show moreThis thesis focused on the evaluation of an eHealth intervention for cognitive stroke rehabilitation and the perspectives of different stakeholders on the uptake of eRehabilitation in general. The studies included in this thesis showed that there was no overall effect of an online brain training programme on cognitive functioning of patients with stroke. Only performances on cognitive function tests that were similar to the games included in the intervention improved, no near transfer effect was found. Moreover, usage of the training was suboptimal and not all of the patients were able to complete it. It would appear important to support stroke patients with CBCR training, since training is not well used by all patients. However, regarding patients’ ICT readiness, wishes and requirements it was also found that a relatively large amount of patients in rehabilitation wish to incorporate ICT in their rehabilitation treatment. In addition, developing tailored implementation strategies to implement eHealth in the bachelor curriculum of health professionals, based on the identified barriers and facilitators in this thesis is highly relevant to make sure that future health professionals are able to work with eHealth. Show less
Résumé de la thèse Cette thèse porte sur le rapport entre communication, pouvoir et violence au Tchad depuis la pénétration coloniale jusqu’à la période postindépendance. Les régions du Moyen... Show moreRésumé de la thèse Cette thèse porte sur le rapport entre communication, pouvoir et violence au Tchad depuis la pénétration coloniale jusqu’à la période postindépendance. Les régions du Moyen-Chari et du Guéra illustrent cette problématique structurant l’interaction communication, pouvoir et violence au Tchad. Ce territoire connut des violences multiformes liées à la mise en place et à l’usage des systèmes de communication. Pendant la colonisation, l’instauration de l’autorité coloniale sur ce vaste territoire avait nécessité la création des voies de communication dont les réalisations ont été dramatiques pour les populations paysannes. Celles-ci étaient astreintes aux corvées de portage des matériels militaires et des travaux forcés. Pendant, les guerres civiles postindépendances, les systèmes de communication ont été intégrés dans les stratégies de violences. Les routes et les divers moyens de l’information et de transport constituent des enjeux stratégiques pour lesquels les forces militaires en guerre projettent la violence sur les populations rurales. Les nouvelles technologies de l’information et de communication révolutionnent l’organisation des forces rebelles et les stratégies de guerre au Tchad sans exclure les violences sur les populations. Cependant, les guerres civiles successives ont gravement impacté sur la conduite de l’appareil étatique tchadien. Show less
In this contribution, we will illustrate the modern-day dynamics of the interplay between the need for expedience and efficiency on the one hand, and the demand for openness, inclusiveness and... Show moreIn this contribution, we will illustrate the modern-day dynamics of the interplay between the need for expedience and efficiency on the one hand, and the demand for openness, inclusiveness and transparency on the other by looking into one of government’s main decision-making processes: the legislative process. Particularly in the field of legislation, the balancing of both efficiency and transparency is of the essence for modern legislatures in parliamentary democracies: laws expressed by acts and legislative instruments can only be truly effective if they rest on broad societal support. As we will argue, a transparent and inclusive legislative process functions as a kind of democratic check on government action: it guarantees sufficient deliberative activity before a government may act. Throughout our contribution, a 2012 comparative study commissioned by the Dutch Ministry of Security and Justice, and carried out by an interdisciplinary team of researchers from Leiden University will be used as a guiding rail to illustrate some the ways in which different jurisdictions in Europe have managed to combine, or at least balance, the need for legislative efficiency and transparency. We will use this study to demonstrate how traditional legislative processes nowadays grapple to translate the will of the citizens into effective legislation, how modern administrations still need democratically underpinned legislative procedures as the basis for the legitimation of (their) decisions, how efficient delivery of decisions and careful (lengthy) scrutiny interact. On the basis of this material we will further discuss concepts of, respectively, efficiency and transparency and especially the way modern legislatures examined in the study use information and communication technology (ICT) to overcome the sometimes opposing demands on their legislative processes. Insofar as possible we will try to highlight a few ‘best practices’ that show how legislative processes can (and cannot) adapt to new present day demands. Show less
Starting with Weber’s disenchantment thesis, a sociological tradition has developed that associates modernity with a crisis of meaning. The de-mystification of our worldview and the decreasing... Show moreStarting with Weber’s disenchantment thesis, a sociological tradition has developed that associates modernity with a crisis of meaning. The de-mystification of our worldview and the decreasing influence of religious traditions in specific are seen as obstacles for making sense of human existence. But in fact, modern societies are full of meaning and they continue to be religious. This study shows that, in an implicit form, religion can be found everywhere in our culture. The Internet hype of the 1990s was a particularly effervescent example of implicit religiosity. The hopeful discourse about the Internet that typified this hype drew on religious ideas and language, and it inspired strong belief. This dissertation explores the appeal of the Internet as an object of faith and it looks at how it could serve as a source of meaning. Show less
Als een ICT-leverancier geen exoneratie in een overeenkomst met zijn klant opneemt, is hij in principe onbeperkt aansprakelijk als hij schade toebrengt bij de uitvoering van een ICT-project. Een... Show moreAls een ICT-leverancier geen exoneratie in een overeenkomst met zijn klant opneemt, is hij in principe onbeperkt aansprakelijk als hij schade toebrengt bij de uitvoering van een ICT-project. Een exoneratie is een clausule in een contract waarmee een leverancier zijn aansprakelijkheid uitsluit of beperkt. Rechters moeten terughoudend zijn met het opzij schuiven van exoneraties die zijn overeengekomen tussen professionele ICT-partijen. Ook als een ICT-leverancier een exoneratie overeenkomt, kunnen er omstandigheden zijn waardoor een rechter die exoneratie terzijde schuift. Deze omstandigheden worden geanalyseerd in dit proefschrift. Eén van de omstandigheden waaronder een leverancier geen beroep mag doen op zijn exoneratie is als hij opzettelijk of met bewuste roekeloosheid schade toebrengt aan zijn klant. Als hiervan geen sprake is, zijn er nog een aantal andere omstandigheden op grond waarvan exoneraties doorbroken kunnen worden. In het proefschrift wordt betoogd dat als geen sprake is van opzet of bewuste roekeloosheid, rechters terughoudend moeten zijn met het opzij schuiven van exoneraties die zijn overeengekomen tussen professionele partijen. Professionele partijen moeten vrij zijn om in hun contracten onderling risico's te verdelen. Exonereren is eigenlijk niets anders dan het verdelen van aansprakelijkheidsrisico's. Show less
Does ICT pervasion of society threaten our legal system? To address the question, four requirements for a sustainable rule of law are discerned: (1) a clear jurisdiction, (2) legitimate rule making... Show moreDoes ICT pervasion of society threaten our legal system? To address the question, four requirements for a sustainable rule of law are discerned: (1) a clear jurisdiction, (2) legitimate rule making, (3) integrity in government and judiciary and (4) stability in society. It is argued that four new and insufficiently understood ICT constructs manifest themselves in society: (a) regulation by ICT architecture, (b) the perception of vanishing resposibilities through ICT complexity, (c) the economic status of reciprocal business models as in open source communities and (d) the emergence of information mountains-monopolies as fostered by Google. All four arguably pose threats to the sustainability of our legal system. Remedies are hard to find - a serious effort in multidisciplinary research and education is advocated. Show less
