In many real-world applications today, it is critical to continuously record and monitor certain machine or system health indicators to discover malfunctions or other abnormal behavior at an early... Show moreIn many real-world applications today, it is critical to continuously record and monitor certain machine or system health indicators to discover malfunctions or other abnormal behavior at an early stage and prevent potential harm. The demand for such reliable monitoring systems is expected to increase in the coming years. Particularly in the industrial context, in the course of ongoing digitization, it is becoming increasingly important to analyze growing volumes of data in an automated manner using state-of-the-art algorithms. In many practical applications, one has to deal with temporal data in the form of data streams or time series. The problem of detecting unusual (or anomalous) behavior in time series is commonly referred to as time series anomaly detection. Anomalies are events observed in the data that do not conform to the normal or expected behavior when viewed in their temporal context.This thesis focuses on unsupervised machine learning algorithms for anomaly detection in time series. In an unsupervised learning setup, a model attempts to learn the normal behavior in a time series — which might already be contaminated with anomalies — without any external assistance. The model can then use its learned notion of normality to detect anomalous events. Show less
The archaeology domain produces large amounts of texts, too much to effectively read or manually search through for research. To alleviate this problem, we created a search system (called AGNES),... Show moreThe archaeology domain produces large amounts of texts, too much to effectively read or manually search through for research. To alleviate this problem, we created a search system (called AGNES), which combines full text search with entity and geographical search. We first created a manually labelled data set to train a Named Entity Recognition model, which is used to extract entities from text. We also did a user requirement study, and usability evaluation on the system, to make sure it is suitable for archaeological research. In a case study on Early Medieval cremations, we show that using AGNES leads to a knowledge increase when compared to the knowledge of experts, gathered using previously available search engines. This shows that this kind of intelligent search system can help with literature research, find more relevant data, and lead to a better understanding of the past. Show less
The manual analysis of remotely-sensed data is a widespread practice in local and regional scale archaeological research, as well as heritage management. However, the amount of available high... Show moreThe manual analysis of remotely-sensed data is a widespread practice in local and regional scale archaeological research, as well as heritage management. However, the amount of available high-quality, remotely-sensed data is continuously growing at a staggering rate, which creates new challenges to effectively and efficiently analyze these data and find and document the seemingly overwhelming number of potential archaeological objects. Therefore, computer-aided methods for the automated detection of archaeological objects are needed. In this thesis, the development and application of automated detection methods, based on Deep Convolutional Neural Networks, for the detection of multiple classes of archaeological objects in LiDAR data is investigated. Furthermore, the implementation of these methods into archaeological practice and the opportunities of knowledge discovery—on both a quantitative and qualitative level—for landscape or spatial archaeology are explored. Show less
Sicho, M.; Liu, X.; Svozil, D.; Westen, G.J.P. van 2021
Many contemporary cheminformatics methods, including computer-aided de novo drug design, hold promise to significantly accelerate and reduce the cost of drug discovery. Thanks to this attractive... Show moreMany contemporary cheminformatics methods, including computer-aided de novo drug design, hold promise to significantly accelerate and reduce the cost of drug discovery. Thanks to this attractive outlook, the field has thrived and in the past few years has seen an especially significant growth, mainly due to the emergence of novel methods based on deep neural networks. This growth is also apparent in the development of novel de novo drug design methods with many new generative algorithms now available. However, widespread adoption of new generative techniques in the fields like medicinal chemistry or chemical biology is still lagging behind the most recent developments. Upon taking a closer look, this fact is not surprising since in order to successfully integrate the most recent de novo drug design methods in existing processes and pipelines, a close collaboration between diverse groups of experimental and theoretical scientists needs to be established. Therefore, to accelerate the adoption of both modern and traditional de novo molecular generators, we developed Generator User Interface (GenUI), a software platform that makes it possible to integrate molecular generators within a feature-rich graphical user interface that is easy to use by experts of diverse backgrounds. GenUI is implemented as a web service and its interfaces offer access to cheminformatics tools for data preprocessing, model building, molecule generation, and interactive chemical space visualization. Moreover, the platform is easy to extend with customizable frontend React.js components and backend Python extensions. GenUI is open source and a recently developed de novo molecular generator, DrugEx, was integrated as a proof of principle. In this work, we present the architecture and implementation details of GenUI and discuss how it can facilitate collaboration in the disparate communities interested in de novo molecular generation and computer-aided drug discovery. Show less
Person re-identification (ReID) methods always learn through a stationary domain that is fixed by the choice of a given dataset. In many contexts (e.g., lifelong learning), those methods are... Show morePerson re-identification (ReID) methods always learn through a stationary domain that is fixed by the choice of a given dataset. In many contexts (e.g., lifelong learning), those methods are ineffective because the domain is continually changing in which case incremental learning over multiple domains is required potentially. In this work we explore a new and challenging ReID task, namely lifelong person re-identification (LReID), which enables to learn continuously across multiple domains and even generalise on new and unseen domains. Following the cognitive processes in the human brain, we design an Adaptive Knowledge Accumulation (AKA) framework that is endowed with two crucial abilities: knowledge representation and knowledge operation. Our method alleviates catastrophic forgetting on seen domains and demonstrates the ability to generalize to unseen domains. Correspondingly, we also provide a new and large-scale benchmark for LReID. Extensive experiments demonstrate our method outperforms other competitors by a margin of 5.8% mAP in generalising evaluation. The codes will be available at https: //github.com/TPCD/LifelongReID. Show less
Visible-infrared person re-identification (VI-ReID) is a challenging and essential task in night-time intelligent surveillance systems. Except for the intra-modality variance that RGB-RGB person... Show moreVisible-infrared person re-identification (VI-ReID) is a challenging and essential task in night-time intelligent surveillance systems. Except for the intra-modality variance that RGB-RGB person reidentification mainly overcomes, VI-ReID suffers from additional inter-modality variance caused by the inherent heterogeneous gap. To solve the problem, we present a carefully designed dual Gaussian-based variational auto-encoder (DG-VAE), which disentangles an identity-discriminable and an identity-ambiguous cross-modalityfeature subspace, following a mixture-of-Gaussians (MoG) prior and a standard Gaussian distribution prior, respectively. Disentangling cross-modality identity-discriminable features leads to more robust retrieval for VI-ReID. To achieve efficient optimization like conventional VAE, we theoretically derive two variational inference terms for the MoG prior under the supervised setting, which not only restricts the identity-discriminable subspace so that the model explicitly handles the cross-modality intra-identity variance, but also enables the MoG distribution to avoid posterior collapse. Furthermore, we propose a triplet swap reconstruction (TSR) strategy to promote the above disentangling process. Extensive experiments demonstrate that our method outperforms state-of-the-art methods on two VI-ReID datasets. Codes will be available at https://github.com/TPCD/DG-VAE. Show less
In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually... Show moreIn 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually. Thus, it becomes challenging to mine semantic information from such a huge amount of visual data. To solve this challenge, deep learning, an important sub-field in machine learning, has achieved impressive developments in recent years. Inspired by its success, this thesis aims to develop new approaches in deep learning to explore and analyze image data from three research themes: classification, retrieval and synthesis. In summary, the research of this thesis contributes at three levels: models and algorithms, practical scenarios and empirical analysis. First, this work presents new approaches based on deep learning to address eight research questions regarding the three themes. In addition, it aims towards adapting the approaches to practical scenarios in real world. Furthermore, this thesis provides numerous experiments and in-depth analysis, which can help motivate further research on the three research themes. Computer Vision Multimedia Applications Deep Learning Show less
