Up to 10% of hospitalized patients have an antibiotic allergy label in their medical file, most frequently concerning penicillins. However, the vast majority of reported allergies to antibiotics... Show moreUp to 10% of hospitalized patients have an antibiotic allergy label in their medical file, most frequently concerning penicillins. However, the vast majority of reported allergies to antibiotics does not represent a "true" allergy but are due to drug intolerance, idiosyncratic reactions or symptoms of the concurrent infectious disease. Since antibiotic allergy labels result in deviation from first-choice antimicrobial therapy, tackling the issue of incorrect antibiotic allergy labelling, already at young age, is a core element of antibiotic stewardship. In this article, we describe the structured approach to the patient with a presumed antibiotic allergy with emphasis on key elements of allergy-specific history taking and the limited risk of cross-allergic reactions between beta-lactam subclasses. Show less
We appreciate the response of Peiffer-Smadja and colleagues to our article confirming the importance of the use of social science to understand antibioticprescription behavior (APB) [1], [2]. In th... Show moreWe appreciate the response of Peiffer-Smadja and colleagues to our article confirming the importance of the use of social science to understand antibioticprescription behavior (APB) [1], [2]. In their letter, Peiffer-Smadja et al. advocate the supplementation of the proposed conceptual framework with insights from cognitive science, most notably cognitive biases[2]. Show less
Warreman, E.B.; Lambregts, M.M.C.; Wouters, R.H.P.; Visser, L.G.; Staats, H.; Dijk, E. van; De Boer, M.G.J. 2019
BackgroundKnowledge of determinants that influence antibiotic prescription behaviour (APB) is essential for the successful implementation of antimicrobial stewardship interventions. The theory of...Show moreBackgroundKnowledge of determinants that influence antibiotic prescription behaviour (APB) is essential for the successful implementation of antimicrobial stewardship interventions. The theory of planned behaviour (TPB) is an established model that describes how cognitions drive human behaviour.ObjectivesThe objective of this study was to identify the sociocultural and behavioural determinants that affect APB and to construct a TPB framework of behavioural intent. Show less
Lambregts, M.M.C.; Bernards, A.T.; Visser, L.G.; Boer, M.G.J. de 2018
