We propose a novel classification method that integrates into existing agile software development practices by collecting data records generated by software and tools used in the development... Show moreWe propose a novel classification method that integrates into existing agile software development practices by collecting data records generated by software and tools used in the development process. We extract features from the collected data and create visualizations that provide insights, and feed the data into a prediction framework consisting of a deep neural network. The features and results are validated against conceptual frameworks that model the development methodologies as similar processes in other contexts. Initial results show that the visualization and prediction techniques provide promising outcomes that may help development teams and management gain better understanding of past events and future risks. Show less
De belangrijkste resultaten van dit proefschrift: de ASAS classificatie criteria voor axSpA blijken robuust en zijn goed toepasbaar in een setting waarbij de waarschijnlijkheid op axSpA lager is... Show moreDe belangrijkste resultaten van dit proefschrift: de ASAS classificatie criteria voor axSpA blijken robuust en zijn goed toepasbaar in een setting waarbij de waarschijnlijkheid op axSpA lager is dan waarin de criteria ontwikkeld zijn. Daarnaast is er op basis van bevindingen in dit proefschrift een belangrijke aanpassing doorgevoerd in een hulpmiddel dat reumatologen begeleidt in het diagnostische proces van (vroege) axSpA. Tevens is het MRI protocol van het SPACE cohort aangepast nadat de toegevoegde waarde van het toedienen van een contrastvloeistof bij het maken van MRI’s nihil bleek te zijn, met als resultaat dat er sinds april 2012 geen MRI’s meer worden gemaakt met de toediening van gadolinium. Dit proefschrift biedt ook adequate handvatten voor verder onderzoek naar de optimale definitie van een positieve MRI. Bovendien worden discrepanties aangaande de beoordeling door verschillende soorten lezers van afwijkingen in de rug (op röntgenfoto’s en MRI’s) aan het licht gebracht waardoor de vraag naar voren komt of training in het onderscheiden van axSpA afwijkingen en afwijkingen die niet gerelateerd zijn aan axSpA van potentiële belang is op de betrouwbaarheid van het beoordelen van afwijkingen in de rug. De onderzoeken in dit proefschrift leveren een bijdrage aan betere herkenning en behandeling van axSpA. Show less
Magnetic resonance imaging (MRI) is sensitive to structural and functional changes in the brain caused by Alzheimer's disease (AD), and can therefore be used to help in diagnosing the disease.... Show moreMagnetic resonance imaging (MRI) is sensitive to structural and functional changes in the brain caused by Alzheimer's disease (AD), and can therefore be used to help in diagnosing the disease. Improving classification of AD patients based on MRI scans might help to identify AD earlier in the disease's progress, which may be key in developing treatments for AD. In this study we used an elastic net classifier based on several measures derived from the MRI scans of mild to moderate AD patients (N = 77) from the prospective registry on dementia study and controls (N = 173) from the Austrian Stroke Prevention Family Study. We based our classification on measures from anatomical MRI, diffusion weighted MRI and resting state functional MRI. Our unimodal classification performance ranged from an area under the curve (AUC) of 0.760 (full correlations between functional networks) to 0.909 (grey matter density). When combining measures from multiple modalities in a stepwise manner, the classification performance improved to an AUC of 0.952. This optimal combination consisted of grey matter density, white matter density, fractional anisotropy, mean diffusivity, and sparse partial correlations between functional networks. Classification performance for mild AD as well as moderate AD also improved when using this multimodal combination. We conclude that different MRI modalities provide complementary information for classifying AD. Moreover, combining multiple modalities can substantially improve classification performance over unimodal classification. (C) 2016 The Authors. Published by Elsevier Inc. Show less
Schouten, T.M.; Koini, M.; Vos, F. de; Seiler, S.; Van der Grond, J.; Lechner, A.; ... ; Rombouts, S.A.R.B. 2016
This work comprises a linguistic survey of the Ancient North Arabian (ANA) epigraphic material from Taymāʾ, conventionally known as Taymanitic (Macdonald 2000: 28-9). A grammatical sketch, based on... Show moreThis work comprises a linguistic survey of the Ancient North Arabian (ANA) epigraphic material from Taymāʾ, conventionally known as Taymanitic (Macdonald 2000: 28-9). A grammatical sketch, based on the linguistic features in the Taymanitic corpus is presented, followed by a discussion of the linguistic features of Taymanitic that are relevant to its linguistic classification. Two appendices follow: a compilation of all previously published inscriptions with grammatical content, and a glossary Show less
Gao, S.; van't Klooster, R.; Wijk, D.F. van; Nederveen, A.J.; Lelieveldt, B.P.F.; Geest, R.J. van der 2015
The Mbam languages of Cameroon have a unique position in Bantu linguistics. Being in between “narrow” Bantu and “wide” Bantu, they sometimes pattern with the one and sometimes with the other, and... Show moreThe Mbam languages of Cameroon have a unique position in Bantu linguistics. Being in between “narrow” Bantu and “wide” Bantu, they sometimes pattern with the one and sometimes with the other, and as such are a rich motherlode for comparative and historical research. The Mbam languages have another point of interest as well. They have been previously analysed as standard 7 vowel languages (/i,e,ɛ,a,ɔ,o,u/) with Advanced Tongue Root (ATR) harmony. While vowel harmony in African languages has received a lot of attention and study, and the vowel-harmony systems of not a few of the Mbam languages have been studied, most of the previous studies have been on individual languages. This study seeks to analyse and compare the vowel systems of ten Mbam languages as a group: both their vowel inventories and their vowel-harmony systems. Various issues in vowel harmony, such as neutral vowels, directionality in and domains of vowel harmony are discussed. This study also proposes a phonological explanation for the functioning of the complex vowel-harmony systems found in the Mbam languages. Finally this study considers the internal classification of the Mbam languages and their position in the wider linguistic context of the Bantu and Bantoid languages. Show less
Hoverflies of the subfamily Microdontinae (Diptera: Syrphidae) have a reputation for causing confusion. Their diversity in shape and size is astonishing: from large, furry-haired species and... Show moreHoverflies of the subfamily Microdontinae (Diptera: Syrphidae) have a reputation for causing confusion. Their diversity in shape and size is astonishing: from large, furry-haired species and convincing wasp-mimics to tiny, unsightly creatures, easily mistaken for something uninteresting. The larvae resemble slugs so much that biologists have described them as molluscs on several occasions. Worldwide, hundreds of species of Microdontinae have been described, but so far there has been no comprehensive attempt to unravel this hotchpotch of names. This thesis examines the phylogenetic relationships of Microdontinae, based on morphological and molecular characters, in order to construct a new classification of the subfamily. A total number of 51 (sub)genera (11 new) are recognized, in which 472 valid species (49 new) are classified, resulting in many new combinations. The newly proposed classification facilitates species level taxonomy. In addition, it should provide a framework for further research on biogeography, (cryptic) speciation and evolution of host specialization. This thesis takes a first shot at some of these subjects by exploring the taxonomy of Neotropical Microdontinae that mimic stingless bees, reviewing and evaluating the associations of these flies with ants, and speculating on their historical biogeography. Show less
Iterson, M. van; Haagen, H.H.H.B.M. van; Goeman, J.J. 2012
