Objective: The aim of this study was to investigate introductions and spread of different HIV-1 subtypes in the Netherlands. Design: We identified distinct HIV-1 transmission chains in the... Show moreObjective: The aim of this study was to investigate introductions and spread of different HIV-1 subtypes in the Netherlands. Design: We identified distinct HIV-1 transmission chains in the Netherlands within the global epidemic context through viral phylogenetic analysis of partial HIV-1 polymerase sequences from individuals enrolled in the ATHENA national HIV cohort of all persons in care since 1996, and publicly available international background sequences. Methods: Viral lineages circulating in the Netherlands were identified through maximum parsimony phylogeographic analysis. The proportion of HIV-1 infections acquired in-country among heterosexuals and MSM was estimated from phylogenetically observed, national transmission chains using a branching process model that accounts for incomplete sampling. Results: As of 1 January 2019, 2589 (24%) of 10 971 (41%) HIV-1 sequenced individuals in ATHENA had non-B subtypes (A1, C, D, F, G) or circulating recombinant forms (CRF01AE, CRF02AG, CRF06-cpx). The 1588 heterosexuals were in 1224, and 536 MSM in 270 phylogenetically observed transmission chains. After adjustments for incomplete sampling, most heterosexual (75%) and MSM (76%) transmission chains were estimated to include only the individual introducing the virus (size = 1). Onward transmission occurred mostly in chains size 2-5 amongst heterosexuals (62%) and in chains size at least 10 amongst MSM (64%). Considering some chains originated in-country from other risk-groups, 40% (95% confidence interval: 36-44) of non-B-infected heterosexuals and 62% (95% confidence interval: 49-73) of MSM-acquired infection in-country. Conclusion: Although most HIV-1 non-B introductions showed no or very little onward transmission, a considerable proportion of non-B infections amongst both heterosexuals and MSM in the Netherlands have been acquired in-country. Show less
This article discusses the first case law issued on the EU-Turkey deal from April to June 2016, which authoritatively answers the question whether Turkey constitutes a safe third country for... Show moreThis article discusses the first case law issued on the EU-Turkey deal from April to June 2016, which authoritatively answers the question whether Turkey constitutes a safe third country for refugees. In 390 out of 393 decisions, the Greek Asylum Appeals Committees ruled that Safe Third Country (STC) requirements were not fulfilled with respect to Turkey, essentially impeding the application of the EU-Turkey deal. Through empirical research, this article sheds light on the reasoning of the decisions of the Appeals Commit- tees and investigates the impact of the EU-Turkey deal on them. This analysis is highly relevant to society today as it aspires to inform further law, policy, and jurisprudence in the field, especially since it provides access to sources that, due to language and other practical barriers, would remain far from the reach of legal and policy experts. Show less
This edited volume focuses on mobile phone use in specific African communities, namely those that have a long history of mobility and are regarded as marginal in the national economic, social and... Show moreThis edited volume focuses on mobile phone use in specific African communities, namely those that have a long history of mobility and are regarded as marginal in the national economic, social and/or political context. It was in such regions that the most intensive dynamics were expected to be seen following the introduction of the mobile phone. Contributions: Introduction: mobile margins and the dynamics of communication (Mirjam de Bruijn, Inge Brinkman and Francis Nyamnjoh); Mobilit‚ et moyens de communication au Gu‚ra (Chad) (Djimet Seli); La connexion des marges: marginalit‚ politique et technologie de d‚senclavement en Basse Casamance (Sud du S‚n‚gal) (Fatima Diallo); 'Angola my country, Cape Town my home': a young migrant's journey of social becoming and belonging (Imke Gooskens); Transnational migration and marginality: Nigerian migrants in anglophone Cameroon (Tangie Nsoh Fonchingong); Les femmes hadjaraye du Gu‚ra … l'‚cole de l'alphab‚tisation (Khalil Alio); From foot messengers to cell phones: communication in Kom, Cameroon, c. 1916-1998 (Walter Gam Nkwi); Grandeur ou misŠres des cabines t‚l‚phoniques priv‚es et publiques au Mali (Naffet Ke‹ta); Informationandcommunication technology and its impact on transnational migration: the case of Senegalese boat migrants (Henrietta Nyamnjoh); Identities of place: mobile naming practices and social landscapes in Sudan (Siri Lamoureux). [ASC Leiden abstract] Show less
