Significance: Particle field holography is a versatile technique to determine the size and distribution of moving or stationary particles in air or in a liquid without significant disturbance of... Show moreSignificance: Particle field holography is a versatile technique to determine the size and distribution of moving or stationary particles in air or in a liquid without significant disturbance of the sample volume. Although this technique is applied in biological sample analysis, it is limited to small sample volumes, thus increasing the number of measurements per sample. In this work, we characterize the maximum achievable volume limit based on the specification of a given sensor to realize the development of a potentially low-cost, single-shot, large-volume holographic microscope.Aim: We present mathematical formulas that will aid in the design and development and improve the focusing speed for the numerical reconstruction of registered holograms in particle field holographic microscopes. Our proposed methodology has potential application in the detection of Schistosoma haematobium eggs in human urine samples.Approach: Using the Fraunhofer holography theory for opaque objects, we derived an exact formula for the maximum diffraction-limited volume for an in-line holographic setup. The proof-of-concept device built based on the derived formulas was experimentally validated with urine spiked with cultured Schistosoma haematobium eggs.Results: Results obtained show that for urine spiked with Schistosoma haematobium eggs, the volume thickness is limited to several millimeters due to scattering properties of the sample. The distances of the target particles could be estimated directly from the hologram fringes.Conclusion: The methodology proposed will aid in the development of large-volume holographic microscopes. (C) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Show less
Why do black holes emit thermal radiation? And how does a closed quantum system thermalize? These apparently unrelated questions might be both connected to an essential feature of quantum... Show moreWhy do black holes emit thermal radiation? And how does a closed quantum system thermalize? These apparently unrelated questions might be both connected to an essential feature of quantum techanics: the dynamics of quantum information and its chaotic properties. Indeed, regardless of the unitary time evolution, quantum information seems to be dissipated. The solution to these contradictions may heavily affect the near future technologies, in light of the recent progresses towards building a quantum computer.In this thesis we investigate the fascinating idea that such chaotic properties leave traces on the late time hydrodynamic excitations. We do this from two opposite directions, both from weakly coupled field theories, using a combination of field theory techniques, and from strongly-coupled field theories, using the AdS/CFT correspondence. Moreover, we studied a fermionic and bosonic quantum critical point, which are 'exotic' states of matter where quantum information plays an important role. The main results of this thesis consist of the formulation of a Boltzmann-like equation for many-body chaos, the discovery of a new property of thermal correlation functions (pole-skipping), and the analysis of which is the correct and meaningful observable to measure experimentally in order to probe quantum chaos. Show less
Phenomenologically, cosmic inflation is a satisfying and well-tested description of the physics of the very early universe. During this epoch, the universe was dominated by high energy phenomena... Show morePhenomenologically, cosmic inflation is a satisfying and well-tested description of the physics of the very early universe. During this epoch, the universe was dominated by high energy phenomena that can only be truly understood in a quantum gravity theory such as string theory. In this thesis we show that the embedding of inflation in a string theoretic framework is very sensitive to the details of the theory. We consider both the low energy supergravity limit as well as a worldsheet set-up. Moreover, we investigate the constraints imposed by supersymmetry and conformal symmetry. Conformal symmetry is important both in the worldsheet theory as well as in a holographic description of inflation. In the latter case we investigate the imprints of conformal invariance on the (observable) statistical correlations in the cosmic microwave background radiation. Show less
