Quantitative and local morphometry of mouse brain MRI is a relatively new field of research, where automated methods can be exploited to rapidly provide accurate and repeatable results. In this... Show moreQuantitative and local morphometry of mouse brain MRI is a relatively new field of research, where automated methods can be exploited to rapidly provide accurate and repeatable results. In this thesis we reviewed several existing methods and applications of quantitative morphometry to brain MR images. The Moore-Rayleigh test is proposed as new method to quantitatively analyze mouse brain MRI using deformation-based morphometry. This method has been validated on multiple datasets and proved to be reliable, accurate and repeatable, without the loss of computational time. Show less