This dissertation contributes to the literature on fathers’ parenting in families with young children using longitudinal, hormonal, and observational data. The results in Chapter 2 demonstrated... Show moreThis dissertation contributes to the literature on fathers’ parenting in families with young children using longitudinal, hormonal, and observational data. The results in Chapter 2 demonstrated that fathers’ hostile and harsh behaviors were related to children’s bullying behavior in elementary school, whereas the effect of the mothers’ behavior was less pronounced. In Chapter 3, the results suggested that fathers’ testosterone is beneficial for the quality of fathers’ parenting (i.e., sensitivity) when fathers’ testosterone reacts in the expected direction given the context of the father-child interaction (i.e., a decrease during a harmonious interaction and an increase during a challenging interaction). The results in Chapter 4 unexpectedly showed that fathers’ sensitivity was largely independent of varying gender-typed contexts. Chapter 5 provided evidence for a specific role of religious fathers, but not mothers, in communicating implicit gender messages and in turn the development of children’s gender attitudes. The most important take-away from this dissertation is that fathers cannot be ignored in child developmental and parenting research, and consequently also in child and family interventions. Show less
Hoekstra, P.T.; Esbroeck, M. van; Dood, C.J. de; Corstjens, P.L.A.M.; Cnops, L.; Zeijl-van der Ham, C.J.G. van; ... ; Lieshout, L. van 2021
Background: In order to evaluate the diagnostic value of schistosome circulating anodic antigen (CAA) detection, serum and urine CAA-levels were determined in a single cluster of 34 Belgian... Show moreBackground: In order to evaluate the diagnostic value of schistosome circulating anodic antigen (CAA) detection, serum and urine CAA-levels were determined in a single cluster of 34 Belgian tourists at three timepoints within a period of 14 weeks following proven Schistosoma exposure in South Africa and compared with two in-house antibody assays. Methods: Samples were collected 4-5 and 7-8 weeks post-exposure and subsequently 5-6 weeks following praziquantel treatment. Schistosoma antibodies were detected by an adult worm antigen-immunofluorescence assay (AWA-IFA) and a soluble egg antigen-enzyme-linked immunosorbent assay (SEA-ELISA), while CAA concentrations were determined by the Up-Converting reporter Particle labelled Lateral Flow (UCP-LF) test. Results: Antibodies were detected in 25/34 (73%) travellers pre-treatment and in 27/34 (79%) post-treatment, with the AWA-IFA showing better performance than the SEA-ELISA. Pre-treatment, CAA was detected in 13/ 34 (38%) and 33/34 (97%) of the travellers in urine and serum, respectively. Post-treatment, all except one traveller became serum CAA negative. This in contrast to the detected antibodies, as well as the previously reported diagnostic results of this cluster. Conclusions: The UCP-LF CAA serum assay has been demonstrated as the most sensitive method for the diagnosis of early Schistosoma infections and post-treatment monitoring in travellers. Show less
This thesis discusses the discovery potential of Intensity Frontier experiments. As a particular examples of such experiment the SHiP and MATHUSLA experiments where taken. The reach of these... Show moreThis thesis discusses the discovery potential of Intensity Frontier experiments. As a particular examples of such experiment the SHiP and MATHUSLA experiments where taken. The reach of these experiments was studied for the number of specific model of the Beyond Standard Model physics, namely neutrino Minimal Standard Model, Higgs-like scalar, axion-like particles and light dark matter. Show less
Willik, D. van der; Pelzer, N.; Algra, A.; Terwindt, G.M.; Wermer, M.J.H. 2017
Discussion: Strictly lobar MBs strongly predict CAA in non-ICH individuals when found in a hospital context. However, their diagnostic accuracy in the general population appears limited. (C) 2015... Show moreDiscussion: Strictly lobar MBs strongly predict CAA in non-ICH individuals when found in a hospital context. However, their diagnostic accuracy in the general population appears limited. (C) 2015 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved. Show less
This is the first time developmental outcome following hearing screening in children with permanent childhood hearing impairment was studied in a unique, pseudo-randomized design. We found that... Show moreThis is the first time developmental outcome following hearing screening in children with permanent childhood hearing impairment was studied in a unique, pseudo-randomized design. We found that early detection of hearing loss by newborn hearing screening (and subsequent early intervention) is beneficial for the development of children with permanent childhood hearing impairment, although their development at 3-5 years is not yet comparable to that of children with normal hearing. We showed that the yield of the current hearing screening program is large, but that there is ample room for improvement in the timing following early detection of hearing loss. We would like to emphasize that the aetiology of permanent childhood hearing impairment should be investigated and the cause taken into account when evaluating the development of the child. Show less
