The Safe by Design (SbD) concept aims to ensure the production, use and disposal of materials and products safely. While there is a growing interest in the potential of SbD to support policy... Show moreThe Safe by Design (SbD) concept aims to ensure the production, use and disposal of materials and products safely. While there is a growing interest in the potential of SbD to support policy commitments, such as the EU Green Deal and the Circular Economy Action Plan in Europe, methodological approaches and practical guidelines on SbD are, however, largely missing. The combined use of Life Cycle Assessment (LCA) and Risk Assessment (RA) is considered suitable to operationalize SbD over the whole life-cycle of a product. Here, we explore the potential of the combined use of LCA and RA at Technological Readiness Level (TRL) 1–6. We perform a review of the literature presenting and/or developing approaches that combine LCA and RA at early stages of product design. We identify that basic early-on-evaluations of safety (e.g., apply lifecycle thinking to assess risk hotspots, avoid use of hazardous chemicals, minimize other environmental impacts from chemicals) are more common, while more complex assessments (e.g., ex-ante LCA, control banding, predictive (eco)toxicology) require specialized expertise. The application of these simplified approaches and guidelines aims to avoid some obvious sources of risks and impacts at early stages. Critical gaps need to be addressed for wider application of SbD, including more studies in the product design context, developing tools and databases containing collated information on risk, greater collaboration between RA/LCA researchers and companies, and policy discussion on the expansion from SbD to Safe and Sustainable by Design (SSbD). Show less
The concepts of Safe by Design (SbD) and Safe and Sustainable by Design (SSbD) are receiving increasing attention. The definitions of both concepts include the term ‘life cycle’ in combination with... Show moreThe concepts of Safe by Design (SbD) and Safe and Sustainable by Design (SSbD) are receiving increasing attention. The definitions of both concepts include the term ‘life cycle’ in combination with the terms ‘chemical’, ‘material’ and ‘product’, but their meanings are not further elaborated and defined in scholarly publications on SbD/SSbD. Here, we address two research questions: (1) How are the terms chemical, material and product used and defined in the scholarly literature on SbD and SSbD; (2) How are life cycles defined and which are considered in the scholarly literature on SbD/SSbD? We found largely consistent, though still confusing, uses of the terms product, material and chemical and we found four types of life cycles in the reviewed papers. Using consistent definitions of the terms product, material and chemical, we reduce the four types of life cycles found to three types of distinctive life cycles: (1) the life cycle of a product; (2) the life cycle of a chemical in a specific product; (3) the life cycle of a chemical in all its product applications. We discuss the different trade-offs that each of these life cycle approaches canidentify and argue that they are complementary and should preferably all be applied in SbD/SSbD studies. Show less
