Conclusion. Our data suggest that the immune cell composition of the synovium and the IFP is similar, and includes activated cells that could contribute to inflammation through secretion of... Show moreConclusion. Our data suggest that the immune cell composition of the synovium and the IFP is similar, and includes activated cells that could contribute to inflammation through secretion of proinflammatory cytokines. Moreover, preliminary analyses indicate that synovial CD4+ T cells might associate with pain in patients with endstage OA of the knee. Show less
Broek, M. van den; Dirven, L.; Kroon, H.M.; Kloppenburg, M.; Ronday, H.K.; Peeters, A.J.; ... ; Allaart, C.F. 2013