Throughout this thesis, I have endeavored to apply an engineer’s mindset in my pursuit to better understand the marvelously convoluted immune system. In doing so, my colleagues and I have generated... Show moreThroughout this thesis, I have endeavored to apply an engineer’s mindset in my pursuit to better understand the marvelously convoluted immune system. In doing so, my colleagues and I have generated a number of new ‘hardware’(i.e., genetically engineered) tools and ‘software’ modules (i.e., custom analyses and models) that enable the investigation of several otherwise difficult-to- study concepts. Although we have used these modules here to study immune responses, I hope they may be utilized as tools and approaches to crack outstanding questions in other fields of research. Show less