Until the 17th century, the Dutch coastal region of Zeeland ranked among Europe's most urbanized areas, driven by thriving international trade networks. People living in this time of flourishing... Show moreUntil the 17th century, the Dutch coastal region of Zeeland ranked among Europe's most urbanized areas, driven by thriving international trade networks. People living in this time of flourishing economy benefitted enormously from it in terms of employment opportunities and working conditions, which were reportedly better than in the rest of the Low Countries. However, the rapid growth of Zeeland's urban centers likely presented increasing challenges for the population in terms of accessing essential resources, including food, clean water, and housing. In the 19th century, Zeeland's economy ultimately faced a significant downturn due to the decline in the maritime trade, leading to a substantial reduction in its urban population. Examining patterns of urbanization and economic histories that differ from the commonly studied thriving industrial contexts in bioarcheological research, as exemplified by Zeeland, is a crucial yet relatively underexplored facet in our efforts to understanding the human past. To address this gap, this study investigates the impact of urbanization on the health of Zeeland's inhabitants over time by analyzing nonspecific stress markers (i.e., cribra orbitalia, porotic hyperostosis, and linear enamel hypoplasia) and chronic maxillary sinusitis in a sample of 246 individuals from three urban sites dating from 1030 to 1800 CE. Our analysis of skeletal remains reveals significant differences in the prevalence of porotic hyperostosis, linear enamel hypoplasia, and sinusitis between the medieval and post-medieval periods. These findings suggest that de-urbanization and economic decline adversely affected the health and well-being of the populations under study, influenced by factors such as working conditions and food availability. This study provides a new perspective on bioarcheological approaches to urbanization, shedding light on the intricate realities of urbanization in Zeeland and offering important insights into its complexities. Show less
Thromboembolic complications remain a major public health burden, making antithrombotic agents one of the most widely prescribed groups of medication, but the treatment is often challenging as it... Show moreThromboembolic complications remain a major public health burden, making antithrombotic agents one of the most widely prescribed groups of medication, but the treatment is often challenging as it at the same time increases risk of bleeding. With nationwide data from Statistics Netherlands, antithrombotic therapy and relevant clinical outcomes were comprehensively examined in the patient population of atrial fibrillation, overall or among those with comorbid cancer. The results suggest the patient population was increasingly receiving anticoagulants, driven by the newly introduced medication- direct oral anticoagulant and guided by the CHA2DS2-VASc score, and meanwhile the patient population experienced fewer ischemic stroke and major bleeding. In spite of these promising changes, suboptimal medication adherence and potential underuse of anticoagulants remain directions for further improvement. Antithrombotic agent use during pregnancy was also examined in the general Dutch pregnant population, which featured a surge in antiplatelet prescriptions, and risk of preeclampsia/eclampsia decreased and several newborn outcomes improved simultaneously. Together, the studies presented in this thesis provide an overview of antithrombotic therapy in the Netherlands in recent years, providing insights for further improving this treatment and relevant patient outcomes. Show less
This dissertation examines the educational positions of children of immigrants in the Netherlands from 1980 to 2020. In particular, the influence of migration background and socioeconomic factors... Show moreThis dissertation examines the educational positions of children of immigrants in the Netherlands from 1980 to 2020. In particular, the influence of migration background and socioeconomic factors on educational positions is studied. Findings reveal substantial progress in education for migrant children overall, especially among the second generation, younger cohorts, and girls with a migrant background, indicating promising upward mobility within the education system for many of these children. The family environment impacts educational outcomes, with socioeconomic background playing a crucial role. Higher parental incomes correlate with higher education levels for children in both the short and long term. Additionally, the living environment affects outcomes such as school dropout rates, especially among boys from migrant backgrounds in larger cities. They are more prone to leaving education prematurely than their female or non-migrant peers. Despite institutional barriers and discrimination within the education system, these children demonstrate an upward trend in education, highlighting the need for further research incorporating discrimination as a factor. Show less
The African Studies Centre Leiden celebrated its 75th anniversary at Museum Volkenkunde in Leiden on 8 September 2022. It was a festive day with colleagues, students, alumni, and societal partners.... Show moreThe African Studies Centre Leiden celebrated its 75th anniversary at Museum Volkenkunde in Leiden on 8 September 2022. It was a festive day with colleagues, students, alumni, and societal partners. This ASCL Occasional Publication presents the keynote speeches of the day, giving insight into the Centre’s rich past and present research, education, library and societal activities. In addition, it is illustrated with many pictures of the day and showcases the ASCL Library’s special items from the collection that were exhibited. Show less
In response to the shortage of nursing staff and the so-called refugee crisis in 2015, two residential homes invited first-generation immigrants with a refugee background to participate in a... Show moreIn response to the shortage of nursing staff and the so-called refugee crisis in 2015, two residential homes invited first-generation immigrants with a refugee background to participate in a project for nursing education, orientation and internships. Between 2015 and 2018, a group of ten immigrants started working in a Dutch residential home and a group of seventeen immigrants in the German home. This dissertation investigates the social processes when these newcomers start working with the established staff, as well as the extent to which their mutual interactions and values of good care influence the enactment of geriatric care. Using ethnographic observations (305 hours), in-depth interviews (44) and six focus groups (24), the established care workers and immigrants were followed in both homes. The empirical data shows that institutional constraints, such as staff shortage, the imposition of professional norms, gossip used as a ‘weapon of the weak’, mutual suspicions of indifference, and collective images of ‘us’ versus ‘them’ affected the enactment of geriatric care. Their habitus stimulated them to tinker among each other as well as with different, sometimes conflicting, values of good care. However, both groups shared the feeling of ignorance by management, a pain of not mattering. Show less
In this project we examine whether homicide ‘clusters together’ with other adverse health outcomes in the Netherlands, focusing on child mortality, suicide, sexual risk behavior, and substance... Show moreIn this project we examine whether homicide ‘clusters together’ with other adverse health outcomes in the Netherlands, focusing on child mortality, suicide, sexual risk behavior, and substance abuse. We expect moderate-to-strong correlations between homicide and the other adverse health phenomena (hypothesis 1). Further, we expect that these correlations will be reduced when social disorganization is controlled for (hypothesis 2).The study used population-level data between the years 1996 and 2019, for each of the 40 local regions of the Netherlands. We applied a multilevel correlation procedure to evaluate correlations between homicide and the other adverse health outcomes. Correlations between homicide and the other adverse health outcomes were modest. That is, we found only limited evidence for clustering between homicide and the other adverse health outcomes. The patterns of clustering that did occur, suggested that social disorganization in the region promotes risk-taking behaviors in the population, which ultimately increases rates of homicide, abuse of illegal drugs and births to adolescent parents.Project materials, syntax and supplementary information can be found on the Open Science Framework at https://osf.io/jd5yu/. Show less
The aim of this chapter is to contribute to the debate on deconstructing the gender binary, toexplore notions of experiencing shame and violence, and also to identify key points of self-concept... Show moreThe aim of this chapter is to contribute to the debate on deconstructing the gender binary, toexplore notions of experiencing shame and violence, and also to identify key points of self-concept ingenderqueer people, by running a survey in three different countries: Greece, the UK and the Netherlands.The survey is the first to explore the impact of this gender- binary discourse and the experience of shameand violence within this frame, within the genderaqueer community in a comparative perspective. Thechapter contributes to the debate on perceptions of masculinity and femininity in association with shameand violence, while reconnoitring the role of culture as a driver of these perceptions and how that role leadsto the re-evaluation of the self along with the sense and impact of shame as a relational process with the self and the society. The survey approaches shame and violence, not only in terms of how they are perceived by the genderqueer community, but also of how they are expressed, e.g. in a passive way (directed violence against a person) or active way (person as actor engaging in violent behaviour) in everyday life. The application of different perspectives on confronting the binary, power and shame provides a critical take on the gender-based debate and on the crux of self-concept and identifies breaks with existing thinking and practice that are essential to any reform of gender recognition policy. Show less
Jonas, P.; Savigne, E.G.; Koster, M.; Choonara, I. 2022
Over the past ten years, seven Dutch Universities have built a sustainable exchange with seven institutes in Cuban healthcare. The exchange was initiated by the Leiden University Medical Centre and... Show moreOver the past ten years, seven Dutch Universities have built a sustainable exchange with seven institutes in Cuban healthcare. The exchange was initiated by the Leiden University Medical Centre and the University of Medical Sciences of Havana. Cooperation with Cuba was chosen as Cuba has excellent primary healthcare and has a strong focus on prevention and public health. These were considered important due to the major contribution of non-communicable diseases to morbidity and mortality in the Netherlands. Exchanges have occurred with Dutch health professionals and students visiting Cuban healthcare institutions and Cuban postgraduate students studying in the Netherlands. There has been an increased awareness of the importance of public health and prevention in Dutch professional organizations following the exchange. The exchange has also helped to break the scientific and economic US blockade of Cuba and resulted in joint publications. In this review we described the process, key aspects, results and lessons learned in this process. Collaboration between Cuba (a middle income) and the Netherlands (a high-income country) is possible. Show less
The impact of COVID-19 on population health is recognised as being substantial, yet few studies have attempted to quantify to what extent infection causes mild or moderate symptoms only, requires... Show moreThe impact of COVID-19 on population health is recognised as being substantial, yet few studies have attempted to quantify to what extent infection causes mild or moderate symptoms only, requires hospital and/or ICU admission, results in prolonged and chronic illness, or leads to premature death. We aimed to quantify the total disease burden of acute COVID-19 in the Netherlands in 2020 using the disability-adjusted life-years (DALY) measure, and to investigate how burden varies between age-groups and occupations. Using standard methods and diverse data sources (mandatory notifications, population-level seroprevalence, hospital and ICU admissions, registered COVID-19 deaths, and the literature), we estimated years of life lost (YLL), years lived with disability, DALY and DALY per 100,000 population due to COVID-19, excluding post-acute sequelae, stratified by 5-year age-group and occupation category. The total disease burden due to acute COVID-19 was 286,100 (95% CI: 281,700-290,500) DALY, and the per-capita burden was 1640 (95% CI: 1620-1670) DALY/100,000, of which 99.4% consisted of YLL. The per-capita burden increased steeply with age, starting from 60 to 64 years, with relatively little burden estimated for persons under 50 years old. SARS-CoV-2 infection and associated premature mortality was responsible for a considerable direct health burden in the Netherlands, despite extensive public health measures. DALY were much higher than for other high-burden infectious diseases, but lower than estimated for coronary heart disease. These findings are valuable for informing public health decision-makers regarding the expected COVID-19 health burden among population subgroups, and the possible gains from targeted preventative interventions. Show less
Heus, E. de; Duijts, S.F.A.; Zwan, J.M. van der; Kapiteijn, E.; Dijkum, E.J.M.N. van; Herpen, C.M.L. van; Merkx, M.A.W. 2022
Introduction: Epidemiological discrepancies exist between rare and common can-cers. The aim of this population-based study was to compare rare versus common adult solid cancers in the Netherlands,... Show moreIntroduction: Epidemiological discrepancies exist between rare and common can-cers. The aim of this population-based study was to compare rare versus common adult solid cancers in the Netherlands, by providing incidence, prevalence and survival rates, evaluating trends in survival and comparing individual entities within domains and families.Methods: All adult patients with malignant solid cancers in the Netherlands between 1995 and 2019 were identified from the Netherlands Cancer Registry. Data on patient, tumour and treatment characteristics were collected, and relative survival and survival trends were ana-lysed.Results: A total of 170,628 patients with rare adult solid cancers and 806,023 patients with common adult solid cancers were included. Rare cancers accounted for 18% of all cancer di-agnoses (mean incidence), and 15% of the total ten-year cancer prevalence during 2010-2019. Overall 5-year survival was worse for rare cancers than for common cancers (52.0% versus 68.7%). Between 1995-1999 and 2015-2019, 5-year survival rates for rare cancers increased to a lesser extent (from 46.2% to 52.6%, i.e. 6.4%) than for common cancers (56.9% Show less
Osong, B.; Masciocchi, C.; Damiani, A.; Bermejo, I.; Meldolesi, E.; Chiloiro, G.; ... ; Soest, J. van 2022
Background and Purpose: Tumor recurrence, a characteristic of malignant tumors, is the biggest concern for rectal cancer survivors. The epidemiology of the disease calls for a pressing need to... Show moreBackground and Purpose: Tumor recurrence, a characteristic of malignant tumors, is the biggest concern for rectal cancer survivors. The epidemiology of the disease calls for a pressing need to improve healthcare quality and patient outcomes. Prediction models such as Bayesian networks, which can probabilistically reason under uncertainty, could assist caregivers with patient management. However, some concerns are associated with the standard approaches to developing these structures in medicine. Therefore, this study aims to compare Bayesian network structures that stem from these two techniques. Materials and Methods: A retrospective analysis was performed on 6754 locally advanced rectal cancer (LARC) patients enrolled in 14 international clinical trials. Local tumor recurrence at 2, 3, and 5-years was defined as the endpoints of interest. Five rectal cancer treating physicians from three countries elicited the expert structure. The algorithmic structure was inferred from the data with the hill-climbing algorithm. Structural performance was assessed with calibration plots and area under the curve values. Results: The area under the curve for the expert structure on the training and validation data was above 0.9 and 0.8, respectively, for all the time points. However, the algorithmic structure had superior predictive performance over the expert structure for all time points of interest. Conclusion: We have developed and internally validated a Bayesian networks structure from experts' opinions, which can predict the risk of a LARC patient developing a tumor recurrence at 2, 3, and 5 years. Our result shows that the algorithmic-based structures are more performant and less interpretable than expert based structures. Show less
This qualitative case study uses a life-course approach to explore syndemic vulnerability in a former fishing village in the Netherlands. Building on four years of fieldwork in a low-income... Show moreThis qualitative case study uses a life-course approach to explore syndemic vulnerability in a former fishing village in the Netherlands. Building on four years of fieldwork in a low-income neighborhood, we explored salient themes between and across families and generations. Elderly community members (> 65 years) were interviewed to map village history and explore how contextual factors have affected family life, health, and wellbeing since the 1940s. We systematically traced and compared processes leading to or from syndemic vulnerability by studying seven families across three generations. Adults with at least one of clustering diseases, their parents (when possible), and their children participated in semi-structured life-course interviews. A complex interaction of endemic social conditions, sociocultural normative processes, learned health be-haviors, and disheartening life events shaped families' predispositions for a syndemic of psychological distress, cardiometabolic conditions, and musculoskeletal pain. Educational attainment, continued social support, and aspirational capabilities emerged as themes related to decreasing syndemic vulnerability. This study demonstrates that syndemic vulnerability is potentially intergenerational and reveals the need for culturally sensitive and family-focused syndemic interventions. Future longitudinal research should focus on unravelling the pathogenesis of the clustering of psychological distress, cardiometabolic conditions, and musculoskeletal pain among young people. Show less
Bertus Haverkort groeide op in een boerengezin in Slagharen. Hij genoot van modernisering op de boerderij van zijn jeugd, omdat dit het werk verlichte en de opbrengsten verbeterde. Met in zijn... Show moreBertus Haverkort groeide op in een boerengezin in Slagharen. Hij genoot van modernisering op de boerderij van zijn jeugd, omdat dit het werk verlichte en de opbrengsten verbeterde. Met in zijn bagage een dosis moderne landbouwkennis uit Wageningen, werkte hij aan programma’s in de tropen waarbij overdracht van westerse kennis het doel was. De aanpak blijkt niet te werken. Hij plaatst vraagtekens bij de toepasbaarheid van de westerse kennis in situaties waar de ecologie, economie en cultuur zoveel verschillen. In samenwerking met lokale deskundigen uit India, Bolivia en Ghana wordt onderzocht hoe lokale wereldbeelden, waarden en kennis een rol spelen. Daarvoor wordt gewerkt aan een onderwijsmethode voor endogene ontwikkeling en aan een benadering voor co-creatie van wetenschappen uit verschillende tradities en wereldstreken. De internationale ervaringen worden in verband gebracht met de huidige crisis in de landbouw in Nederland en monden uit een pleidooi voor klimaat- en natuurvriendelijke landbouw. Show less
Jongenelen, R.G.L.; Leighton, T.; Veldkamp, F. 2022
Afscheidscollege van Prof. dr. Gert J. Oostindie Directeur van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde (KITLV-KNAW) Hoogleraar Koloniale en Postkoloniale Geschiedenis aan de... Show moreAfscheidscollege van Prof. dr. Gert J. Oostindie Directeur van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde (KITLV-KNAW) Hoogleraar Koloniale en Postkoloniale Geschiedenis aan de Universiteit Leiden uitgesproken op vrijdag 17 december 2021 Show less
Broecks, K.; Jack, C.; ter Mors E.; Boomsma, C.; Shackley, S. 2021
Carbon Capture and Storage at industrial processes (industrial CCS) is expected to play an important role in reducing industrial CO2 emissions in the short term. Industrial CCS involves capturing... Show moreCarbon Capture and Storage at industrial processes (industrial CCS) is expected to play an important role in reducing industrial CO2 emissions in the short term. Industrial CCS involves capturing CO2 from industrial processes, such as steel and cement making, and storing the CO2 underground. This study examined the public opinion of industrial CCS through an informed opinion survey in the Netherlands (N = 987) and the United Kingdom (UK; N = 974). On average, respondents were neutral to slightly positive about the implementation of industrial CCS in their country. UK respondents were slightly more positive (M = 4.66 on a 7-point scale) than Dutch respondents (M = 4.38). Awareness and perceived knowledge levels were somewhat higher in the Netherlands than in the UK. In both countries, perceived outcomes of industrial CCS (e.g. for climate change; safety; employment) were strongly associated with industrial CCS opinion, when compared to socio-demographics, proximity to industry (actual and perceived), and psychological variables. Differences between countries in outcome perceptions occur. For example, the safety of CO2 transport is a larger concern in the Netherlands than in the UK, while cost-control is a larger concern in the UK than in the Netherlands. These findings suggest that the national context for CCS implementation matters. Our research suggests that public engagement strategies will benefit from focusing on the economic and climate impacts of industrial CCS, as well as from building trust in industry and addressing perceived safety concerns surrounding different aspects of industrial CCS. Show less
Homicide is generally considered the most serious of all crimes and according to this line of reasoning, constitutes the “tip of the iceberg” of underlying crime. As such, homicide is frequently... Show moreHomicide is generally considered the most serious of all crimes and according to this line of reasoning, constitutes the “tip of the iceberg” of underlying crime. As such, homicide is frequently used as an indicator of the level of violence in cross-national and historical studies. The same could be said for drug-related homicide, specifically. Many drug-related violent incidents remain unreported – including torture, physical assault, threats and so on. In the absence of a full picture of the level of drug-related violence, it can be necessary to use other related indicators for which data is more readily available such as drug-related homicide (DRH). From this perspective, DRH would form a lethal tip of the iceberg of underlying drug-related criminal violence, which in turn could be an indicator of underlying drug market activity. If we indeed consider drug-related homicide as a tip of the iceberg of underlying criminal violence, then we would expect such homicides to cluster together in time and space with other types of criminal violence – in particular firearm-related homicides and other, non-lethal firearm incidents.In this working paper we seek to assess to what extent DRH cluster together with firearm- related violence and whether these forms of violence could be used as indicators of underling drug crime. Show less
This study describes how the interpretations, aspirations and school identity development of Islamic primary schools developed in the period 1988-2013. It gives an overview of the most important... Show moreThis study describes how the interpretations, aspirations and school identity development of Islamic primary schools developed in the period 1988-2013. It gives an overview of the most important turning points for Islamic education and how these turning points have influenced identity development.In this study, the administrators and directors of Islamic primary schools who have at least 10 years of experience in identity development are interviewed. This research shows how complex and diverse the identity of Islamic primary schools is. The main internal and external factors and actors that have influenced the development of school identity are discussed. National and international events have led to a social debate in which the role of Islamic primary schools regarding the integration of Muslims has been questioned. Partly because of this negative attention, Islamic schools have changed from introverted to extroverted organisations. This discussion has also led to unequal treatment of these schools. This research shows precisely how important these schools are for the emancipation of Muslims in the Netherlands. After all, Muslims themselves take the responsibility for education. Islamic primary schools are typical Dutch schools that make an important contribution to a safe pedagogical climate. Show less
Although the Netherlands remained neutral during the First World War, its population was nonetheless affected by the war. Already in the 1920s and 1930s, Dutch journalists wrote about the... Show moreAlthough the Netherlands remained neutral during the First World War, its population was nonetheless affected by the war. Already in the 1920s and 1930s, Dutch journalists wrote about the possibility of a war in which the Netherlands would also be involved. From the early 1920s to the German invasion in May 1940, journalists, political commentators, politicians, military officials and civilians were occupied by the question what tomorrow’s war might look like. This book captures their efforts and brings to life the cultural memories of the First World War and the expectations for the war to come.By focusing on the dynamics of cultural memories, predictions for the future, and the resultant fear and anxiety, this book provides a better understanding of the ways in which the cultural memories of the Great War and expectations for a future war were part of Dutch society. It draws from a wide array of sources, ranging from newspaper clippings, novels, films and theatre plays to political cartoons and paintings. Most importantly, this study has a unique perspective. Whereas most existing studies look back from the Second World War, this book instead looks forward from the interbellum. Show less
