Innovation is often an object of study in economics and management. However, the social and behavioral aspects of innovation acceptance are as important as the economics of product development. A... Show moreInnovation is often an object of study in economics and management. However, the social and behavioral aspects of innovation acceptance are as important as the economics of product development. A significant portion of the literature considers innovation as a change in the way social actions are conducted, entailing a wide range of social, economic, behavioral, and institutional changes. Various approaches have given rise to the need for a typology. Sundbo (1998) divided innovation into three groups depending on the aspects of the phenomenon: theory of entrepreneurship, technological and social aspects, and strategic aspects. Adopting Sundbo's conceptual framework, this study supplemented and developed it based on recent literature that appeared after 1998. Moreover, this study added new directions at the second level of decomposition and the relationships between different aspects of innovation. In particular, this study analyzed phenomena such as open innovation, agile innovation, and “helix” models. Thus, this study developed a novel typology of innovation that expands the theoretical knowledge in this field. Based on these findings, this study proposed promising areas for future innovation studies. Show less
The eighteenth-century passion to order and systematize as well as to measure and calculate has been explained as a result of both the Scientific Revolution and the emergence of centralized states.... Show moreThe eighteenth-century passion to order and systematize as well as to measure and calculate has been explained as a result of both the Scientific Revolution and the emergence of centralized states. The first, enabled the new experimental philosophy that quantified the 'sciences', while the latter created the need for statistics (e.g., demographic data). This paper explores the diffusion of the ‘quantifying spirit’ among the wider public in the eighteenth century and offers alternative explanation for the interest of the population at large in structured quantitative data. Using a corpus of 188 handwritten chronicles, produced by a heterogenous group of middle-class authors from the Low Countries, between 1500-1800, it analyses how early modern chroniclers used Western/Hindu-Arabic numerals in their writings, and under which circumstances this changed in the eighteenth century. From the analysis it appears that chroniclers used meteorological measurement and demographic data for different purposes than natural philosophers and (centralized) governments. Moreover, it transpires that the collection of quantitative data was initially stimulated by local governments, subsequently made public by various media, and picked up by the society at large and higher authorities. Show less
De mogelijke vernieuwingen bij de vreemde talen kunnen resulteren in meer aandacht voor inhoud op het gebied van taal en cultuur. Hoe kun je deze onderdelen geïntegreerd toetsen met taalvaardigheid... Show moreDe mogelijke vernieuwingen bij de vreemde talen kunnen resulteren in meer aandacht voor inhoud op het gebied van taal en cultuur. Hoe kun je deze onderdelen geïntegreerd toetsen met taalvaardigheid? Nivja de Jong, Janine Berns en Tessa Mearns maken in ‘Toetsing als vertrekpunt voor vernieuwing’ creatief gebruik van de bekende driehoek van Biggs (1996) met leerdoelen, toetsing en feedback en leeractiviteiten. Eigenlijk staan de leerdoelen bovenaan, maar als je begint bij de toetsing heb je een veel concreter uitgangspunt. En als het goed is zijn de toetsen valide operationaliseringen van de leerdoelen. De Jong, Berns en Mearns anticiperen op de nieuwe examenprogramma’s voor de moderne vreemde talen en schetsen de voordelen als de leesteksten niet meer over alle mogelijke vakvreemde onderwerpen gaan waar de docenten geen verstand van hebben en die er in feite niet toe doen, maar over taal en cultuur, het vakgebied van de vreemdetaaldocent. De inhoud wordt dan net zo belangrijk als de taal, zoals bij tweetalig onderwijs (CLIL). Daar moet het leerproces, dus ook de feedback en de beoordeling door de docent, zich richten op inhoud én op de taal. Van de CLIL-ervaringen kunnen de vernieuwde talenvakken leren. Show less
In de topsectoren spelen we een rol in een bijzonder soort innovatie: innovatie die plaatsvindt binnen publiek-private samenwerkingen. Deze triple helix bestaat uit overheid, bedrijfsleven en... Show moreIn de topsectoren spelen we een rol in een bijzonder soort innovatie: innovatie die plaatsvindt binnen publiek-private samenwerkingen. Deze triple helix bestaat uit overheid, bedrijfsleven en kennisinstellingen die elk hun eigen vraagstukken en belangen hebben, maar elkaar vinden bij het zoeken naar oplossingen voor maatschappelijke vraagstukken. Steeds vaker wordt dit model aangevuld met de burger als vierde element in de zogenaamde quadruple helix.Vaak is in deze samenwerkingen de overheid op een of andere manier financier. Echter, de overheid is ook een echte belanghebbende, op meerdere manieren. Natuurlijk bewaakt de overheid de maatschappelijke uitdagingen. Maar de overheid maakt ook beleid, bepaalt contouren van wat er wel en niet kan, en formuleert specifiek regels. Hiermee vormt de overheid als geen ander het speelveld waarin innovatie zich kan voltrekken.Deze publicatie gaat over die rol van de overheid bij innovatie. Meer specifiek gaat dit document over de invloed van beleid en wet- en regelgeving op logistieke innovaties. Een recent voorbeeld (mei 2021) omtrent de toelating tot de openbare weg van de Super EcoCombi vrachtwagen laat zien dat de overheid hierbij een belangrijke rol speelt.We hadden behoefte, in de Topsector Logistiek, om beter te begrijpen hoe vanuit de academische expertise die de overheid en overheidsbeleid centraal stelt – de bestuurskunde – naar de rol van de overheid als wegbereider voor innovatie gekeken wordt. Daarmee willen we over veelgehoordekritiek op de rol van de overheid heenstappen, en toewerken naar een reëel beeld van wat van de overheid verwacht mag en kan worden. Daarvoor hebben we een conceptueel kader nodig, waarmee we naar voorkomende problemen kunnen gaan kijken.Prof. Bram Klievink heeft in zijn bijdrage een flinke stap gezet in dit debat. Hij wijst op het belang van integraliteit, afstemming, en coördinatie tussen beleid en uitvoering als belangrijke richtsnoeren voor het beoordelen van effectief beleid voor logistieke innovatie. Zijn suggestie voor het ontwikkelen van adaptief beleid helpt in mijn optiek zowel de overheid als de verschillende belanghebbenden aan de kant van het bedrijfsleven om de discussie op een constructieve manier te vervolgen.prof. dr. Albert Veenstra Scientific Director TKI Dinalog Show less
Hassani, R.T.J.; Sandali, O.; Ouadfel, A.; Packer, M.; Romano, F.; Thuret, G.; ... ; Baudouin, C. 2020
Phacoemulsification is the most frequently performed surgery in the world. Over the past few years, this surgery seems to have reached a plateau with no further innovative breakthroughs. In this... Show morePhacoemulsification is the most frequently performed surgery in the world. Over the past few years, this surgery seems to have reached a plateau with no further innovative breakthroughs. In this paper, we focus on alternatives techniques, the latest innovations, and the research and development pipeline in this field. (C) 2020 Elsevier Masson SAS. All rights reserved. Show less
Durez, P.; Hoekema, A.; Huizinga, T.; Gazin, M.; Present, E.; Veelaert, D.; ... ; Westhovens, R. 2020
A better understanding of disease pathology, improvements in relevant disease outcomes, better treatment strategies and the development of novel therapies all contribute to improving healthcare and... Show moreA better understanding of disease pathology, improvements in relevant disease outcomes, better treatment strategies and the development of novel therapies all contribute to improving healthcare and treatment options. However, the global drug development model today is under increasing pressure, with very high drug development costs. Collaborative research is critical for bringing together different capabilities and expertise to increase the success of drug development, and large-scale collaborations with multiple partners are becoming increasingly common. Research clusters supported by local governments play an important role in bringing together academic centres, hospitals, scientists, and pharmaceutical and biotechnology industries. The 'triple helix' model, with academia, industry and governments working together, has been an important factor in the successful development of novel therapies. During the past 20 years, Galapagos has worked closely with academic centres, hospitals, governments and pharmaceutical companies to conduct innovative research and to develop a novel therapy for rheumatoid arthritis. These collaborations have brought unique knowledge, expertise and skills together, as well as crucial funding at various stages. Local governments in the Benelux have operated in this triple helix model to provide the necessary environment and to stimulate companies to achieve innovation through collaboration. Although the triple helix has already proved successful, evolution to a quadruple helix that includes patients and patient representatives could be the next step to ensure innovation remains transformational. Show less
Background The Idea, Development, Exploration, Assessment and Long-term study (IDEAL) framework was created to provide a structured way for assessing and evaluating novel surgical techniques and... Show moreBackground The Idea, Development, Exploration, Assessment and Long-term study (IDEAL) framework was created to provide a structured way for assessing and evaluating novel surgical techniques and devices. Objectives The aim of this paper was to investigate the utilization of the IDEAL framework within neurosurgery, and to identify factors influencing implementation. Methods A bibliometric analysis of the 7 key IDEAL papers on Scopus, PubMed, Embase, Web of Science, and Google Scholar databases (2009-2019) was performed. A second journal-specific search then identified additional papers citing the IDEAL framework. Publications identified were screened by two independent reviewers to select neurosurgery-specific articles. Results The citation search identified 1336 articles. The journal search identified another 16 articles. Following deduplication and review, 51 relevant articles remained; 14 primary papers (27%) and 37 secondary papers (73%). Of the primary papers, 5 (36%) papers applied the IDEAL framework to their research correctly; two were aligned to the pre-IDEAL stage, one to the Idea and Development stages, and two to the Exploration stage. Of the secondary papers, 21 (57%) explicitly discussed the IDEAL framework. Eighteen (86%) of these were supportive of implementing the framework, while one was not, and two were neutral. Conclusion The adoption of the IDEAL framework in neurosurgery has been slow, particularly for early-stage neurosurgical techniques and inventions. However, the largely positive reviews in secondary literature suggest potential for increased use that may be achieved with education and publicity. Show less
Surveys show that zoo-housed great apes occasionally interact with local wildlife. Bonobos and chimpanzees interact aggressively with and sometimes consume wildlife. Gorillas may also interact with... Show moreSurveys show that zoo-housed great apes occasionally interact with local wildlife. Bonobos and chimpanzees interact aggressively with and sometimes consume wildlife. Gorillas may also interact with local wildlife, but less often in an aggressive way and consumption was rare. Here we report the case of an adolescent female western lowland gorilla in Apenheul Primate Park (Apeldoorn, The Netherlands) that persistently catches and handles ducklings. Prior to observation we proposed four possible explanations, which are not mutually exclusive: play, meat eating, need for abnormal plucking, and allomothering. We saw the female catch ducklings at eight occasions (9 ducklings in total) and she handled ducklings (at least 19) on ten out of 17 observation days. Ad libitum observations showed that the female spent much time plucking the feathers of the duckling, handling it carefully. In addition, she regularly placed a duckling on her back during locomotion. Eating of a carcass was not observed and playing with a carcass was very rare. Based on these observations, we propose that not meat eating and play, but allomothering and abnormal plucking may explain this idiosyncratic behavior. This female probably invented the behavior herself. Show less
Due to the conglomeration of media and publishing companies in the twentieth century (McCleery, 2007), the size of publishing companies has become more polarized, with a majority of small... Show moreDue to the conglomeration of media and publishing companies in the twentieth century (McCleery, 2007), the size of publishing companies has become more polarized, with a majority of small publishers comprising a small percent of revenue and market share compared to the few, but powerful, larger publishing houses (Publishers Association, ‘UK Book Publishing Industry in Statistics’ 2014). In economics, the polarizing principle asserts that ‘developments at one pole of the corporate/cultural spectrum are often counterbalanced by antithetical innovations at the other’ which has, in the publishing industry, led to ‘the emergence of tiny publishing houses’ at the other end of the spectrum in opposition to the conglomerates (Brown et al 2006). This article examines the distribution and disruption of power in the publishing industry by emphasising the role of the small press. Through interview data with small publishers in the United Kingdom, this article considers the power of the small press. Ultimately this article argues that small publishing companies disrupt the power of the conglomerates in the publishing industry by innovation—a characteristic of the entrepreneurially-oriented small firm. By using Johannessen’s six categories of newness (2001), this article illustrates the ways in which small publishers are using innovation to disrupt power in the book industry. Show less
