Leiden University Scholarly Publications

Kassa, D.; Ran, L.; Jager, W. de; Broek, T. van den; Jacobi, R.; Mekonen, M.; ... ; Baarle, D. van 2016

Discriminative expression of whole blood genes in HIV patients with latent and active TB in Ethiopia

Article / Letter to editor

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Conclusions: We showed that five genes (CD8A, TIMP2, CCL22, FCGR1A and TNFRSF1A), specifically FCGR1A and CCL22 have the potential to discriminate active TB from non-active TB in HIV patients in... Show moreConclusions: We showed that five genes (CD8A, TIMP2, CCL22, FCGR1A and TNFRSF1A), specifically FCGR1A and CCL22 have the potential to discriminate active TB from non-active TB in HIV patients in Ethiopia and could be used to improve diagnostic tools for active TB in HIV patients, and to understand the pathogenesis of TB/HIV coinfection. (C) 2016 Published by Elsevier Ltd. Show less