Undoubtedly, grapes and wine are globally the most important fruit and food commodities, respectively. The first objective of this research is to optimize an extraction protocol suitable for grape... Show moreUndoubtedly, grapes and wine are globally the most important fruit and food commodities, respectively. The first objective of this research is to optimize an extraction protocol suitable for grape metabolic profiling followed by the application of that protocol to perform metabolic characterization of grape cultivar, wine types, and vintage using NMR spectroscopy in combination with chemometrics methods. This approach was also used to study different physiological processes in grapevine like ripening of berry and resistance against fungal pathogen. Metabolic characterization of different white wines to highlight the metabolites responsible for sensory attributes was also carried out. Another task of this research was to correlate the metabolic profiling data from grapes and wine with the bioactivity data using various multivariate regression models. Show less