Objective: About 1:650–1,000 children are born with an extra X or Y chromosome (XXX; XXY; XYY), which results in a sex chromosome trisomy (SCT). This study aims to cross-sectionally investigate the... Show moreObjective: About 1:650–1,000 children are born with an extra X or Y chromosome (XXX; XXY; XYY), which results in a sex chromosome trisomy (SCT). This study aims to cross-sectionally investigate the impact of SCT on early social cognitive skills. Basic orienting toward social cues, joint attention, and theory of mind (ToM) in young children with SCT were evaluated. Method: About 105 children with SCT (range: 1–7 years old) were included in this study, as well as 96 age-matched nonclinical controls. Eyetracking paradigms were used to investigate the eye gaze patterns indicative of joint attention skills and orienting to social interactions. The ToM abilities were measured using the subtest ToM of the Developmental NEuroPSYchological Assessment, second edition, neuropsychological test battery. Recruitment and assessment took place in the Netherlands and in the United States. Results: Eyetracking results revealed difficulties in children with SCT in social orienting. These difficulties were more pronounced in children aged 3 years and older, and in boys with 47,XYY. Difficulties in joint attention were found over all age groups and karyotypes. Children with SCT showed impairments in ToM (26.3% in the [well] below expected level), increasing with age. These impairments did not differ between karyotypes. Conclusions: An impact of SCT on social cognitive abilities was found already at an early age, indicating the need for early monitoring and support of early social cognition. Future research should explore the longitudinal trajectories of social development in order to evaluate the predictive relationships between social cognition and outcome later in life in terms of social functioning and the risk for psychopathology. Show less
Children spend most of their days interacting with their social environment. Emotions form a large part of these interactions and vice versa social emotions become meaningful when interacting... Show moreChildren spend most of their days interacting with their social environment. Emotions form a large part of these interactions and vice versa social emotions become meaningful when interacting with others. Understanding the emotion processes that underlie successful social functioning is important, especially in children that experience difficulties in social-emotional functioning such as children with Autism Spectrum Disorders (ASD). These studies used a unique approach towards understanding the complex mechanisms that are involved in emotion processing, incorporating how emotions are perceived, experienced, regulated, and expressed. Sensitive and direct measures of emotion processing such as eyetracking and physiology revealed for the first time on a neurobiological level that children with ASD have difficulties emotionally resonating with others, use less efficient strategies to regulate their emotions, and provided evidence for a possible discordance between the expression and experience of emotions. The preschool years also presented with a possible window of opportunity; children with ASD do feel emotions when it comes to their own experiences and the development of social attention towards others might be prone to improvements during the preschool years. These findings are important to parents and professional and enhance the understanding of emotion processing during these very early years of life. Show less
The function of pitch movements varies across languages. Tone languages, such as Mandarin Chinese, use pitch configurations to differentiate between word forms. For non-tone languages (such as... Show moreThe function of pitch movements varies across languages. Tone languages, such as Mandarin Chinese, use pitch configurations to differentiate between word forms. For non-tone languages (such as Dutch and English), pitch information is mainly used at the post-lexical level, e.g., to signal sentential prominence or delimit prosodic constituents. Therefore, learning to use lexical tones is always difficult for non-tone second language learners of Mandarin who are not familiar with using pitch information in a lexically contrastive way. This thesis investigates various aspects of production and perception of tones by beginning and advanced Dutch learners of Mandarin. Through a series of four experiments, this thesis examines the developmental path of Dutch learners of Mandarin at the university level in their acquisition of fine-grained tonal coarticulation patterns, distribution of attention between segments and tones, phonological processing of tones and using tonal information in spoken word recognition. The mechanisms underlying the learners’ tone acquisition are discussed with reference to current theories and models of second language acquisition and spoken word recognition. Show less
Spoken communication involves transmission of a message which takes physical form in acoustic waves. Within any given language, acoustic cues pattern in language-specific ways along language... Show moreSpoken communication involves transmission of a message which takes physical form in acoustic waves. Within any given language, acoustic cues pattern in language-specific ways along language-specific acoustic dimensions to create speech sound contrasts. These cues are utilized by listeners to discriminate between possible messages intended by the speaker. It is well documented that individual listeners attend to different acoustic cues in different ways. For example, adult second-language (L2) learners often have trouble distinguishing certain L2 speech contrasts. Yet, the question of how listeners come to utilise certain cues and not others for discrimination is not yet well understood. The relationship between this continuous and inherently noisy acoustic signal and the discrete nature of the underlying messages forms the basis for this thesis. I used electrophysiological (EEG) and behavioural measures to investigate how allophonic tonal variants and sub-phonemic features are processed during Mandarin and Dutch speech production, visual processing of written words and reading aloud. In addition, using the visual world eyetracking paradigm, I investigated how the degree of variation (statistical noise) in the acoustic signal affects perception of Cantonese segment and tone contrasts. Show less
