This thesis aimed to evaluate and improve the risk stratification of outpatient management in acute pulmonary embolism (PE) patients. In addition, this thesis aimed to establish current patterns of... Show moreThis thesis aimed to evaluate and improve the risk stratification of outpatient management in acute pulmonary embolism (PE) patients. In addition, this thesis aimed to establish current patterns of home treatment and to assess the safety of anticoagulant treatment in PE patients. Finally, this thesis aimed to provide an overview of outpatient treatment of venous thromboembolism (VTE) in cancer patients at high risk of adverse events. Show less
Easwaran, R.; Khan, M.; Sancheti, P.; Shyam, A.; Bhandari, M.; Ranawat, A.S.; ... ; Rajgopal, A. 2022
Purpose There is a lack of consensus regarding need for Venous Thrombo Embolism (VTE) prophylaxis following arthroscopic knee surgery and open soft tissue knee reconstruction. Clear cut guidelines... Show morePurpose There is a lack of consensus regarding need for Venous Thrombo Embolism (VTE) prophylaxis following arthroscopic knee surgery and open soft tissue knee reconstruction. Clear cut guidelines like ones for trauma surgery and arthroplasty do not exist and the published literature is limited to case reports with a few society guidelines. Given this lack of consensus, we conducted a modified Delphi questionnaire of international experts to provide recommendations on this topic. Methods The consensus statements were generated using an anonymised 3 round modified Delphi questionnaire, sent to an international panel of 38 knee surgeons, with an 80% agreement being set as the limit for consensus. The responses were analysed using descriptive statistics with measures like mode, median and box plots. Feedback was provided to all panelists based on responses from the previous rounds to help generate the consensus. Results Six consensus statements were generated after the three rounds of Delphi. Patient factors, prolonged surgery duration and family history of thrombogenic events emerged as the main points to be taken into consideration for prophylaxis. Conclusion It was established through this study, that there exists a select group of patients undergoing arthroscopic surgery that justify the usage of VTE prophylaxis. The expert responses to most of the questions in different scenarios favoured usage of VTE prophylaxis based on patient factors like advanced age, past history of VTE, smoking, oral contraceptive use etc. Show less
