A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such... Show moreA P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings to directly spell characters using eye-gazes, thereby building communication between the human brain and a computer. Unfortunately, P300 spellers are still not used in human’s daily life and remain in an experimental stage at research labs. The reason for this situation is that the performance and the efficiency of current P300 spellers are unacceptably low for BCI users in their daily life. Therefore, in this thesis, we have focused our attention on developing high performance and efficient P300 spellers in order to bring P300 spellers into practical use. More specifically, in order to increase the performance of a P300 speller, we have developed methods to increase the character spelling accuracy and the Information Transfer Rate. In order to improve the efficiency of a P300 speller, we have developed methods to reduce the number of sensors needed to acquire EEG signals as well as to reduce the complexity of the classifier used in a P300 speller without losing the performance. Show less