Leiden University Scholarly Publications

Lierop, A.H.J.M. van 2013

Sclerostin : a key regulator of bone metabolism

Doctoral Thesis

open access

2015-02-14T00:00:00Z; 2014-01-01T00:00:00Z; 2015-02-14T00:00:00Z; 2014-10-01T00:00:00Z; 2013-05-01T00:00:00Z

In this thesis we studie the role of sclerostin in bone metabolism. We studied patients with the rare bone sclerosing disorders sclerosteosis and van Buchem disease, both caused by sclerostin... Show moreIn this thesis we studie the role of sclerostin in bone metabolism. We studied patients with the rare bone sclerosing disorders sclerosteosis and van Buchem disease, both caused by sclerostin deficiency. We further studied the role of sclerostin in different bone related disorders. Show less