Leiden University Scholarly Publications

Ronen, I.; Webb, A.G. 2023

1H NMR spectroscopy of strongly J-coupled alcohols acquired at 50 mT (2 MHz) using a Carr-Purcell-Meiboom-Gill echo technique

Article / Letter to editor

open access

We have investigated an approach for obtaining H-1 NMR spectra of different alcohols on a large-bore (27 cm diameter), B (0) = 0.05 T (f (0) = 2 MHz) portable MRI scanner. We used a Carr-Purcell... Show moreWe have investigated an approach for obtaining H-1 NMR spectra of different alcohols on a large-bore (27 cm diameter), B (0) = 0.05 T (f (0) = 2 MHz) portable MRI scanner. We used a Carr-Purcell-Meiboom-Gill (CPMG) sequence to acquire multiecho data from solutions of different alcohols, focusing on ethanol, a molecule of relevance to many applications in the food and beverage industry. Our results show that the Fourier transformed J-spectra at different echo spacings fit well with simulations of the evolution of the echo train signal with excellent signal to noise ratio (SNR) for concentrations of similar to 10 % within a few minutes. Spectra were also obtained from intact bottles of whiskey and wine. Finally, we show that different alcohols with similar chemical structures can be differentiated using this approach. Show less