The shear flow of two-dimensional foams is probed as a function of shear rate and disorder. Disordered, bidisperse foams exhibit strongly shear rate dependent velocity profiles. This behavior is... Show moreThe shear flow of two-dimensional foams is probed as a function of shear rate and disorder. Disordered, bidisperse foams exhibit strongly shear rate dependent velocity profiles. This behavior is captured quantitatively in a simple model based on the balance of the time-averaged drag forces in the system, which are found to exhibit power-law scaling with the foam velocity and strain rate. Disorder makes the scaling of the bulk drag forces different from that of the local interbubble drag forces, which we evidence by rheometrical measurements. In monodisperse, ordered foams, rate independent velocity profiles are found, which lends further credibility to this picture. Show less
Heterogeneities in the cell membrane due to coexisting lipid phases have been conjectured to play a major functional role in cell signaling and membrane trafficking. Thereby the material properties... Show moreHeterogeneities in the cell membrane due to coexisting lipid phases have been conjectured to play a major functional role in cell signaling and membrane trafficking. Thereby the material properties of multiphase systems, such as the line tension and the bending moduli, are crucially involved in the kinetics and the asymptotic behavior of phase separation. In this Letter we present a combined analytical and experimental approach to determine the properties of phase-separated vesicle systems. First we develop an analytical model for the vesicle shape of weakly budded biphasic vesicles. Subsequently experimental data on vesicle shape and membrane fluctuations are taken and compared to the model. The parameters obtained set limits for the size and stability of nanodomains in the plasma membrane of living cells. Show less