Leiden University Scholarly Publications

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The predictive value of models of neuromuscular disorders to potentiate clinical translation
Dysregulated mitochondrial metabolism upon cigarette smoke exposure in various human bronchial epithelial cell models
The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds.
Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue
Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish
Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy
Moving neuromuscular disorders research forward: from novel models to clinical studies
Improving translatability of preclinical studies for neuromuscular disorders: lessons from the TREAT-NMD Advisory Committee for Therapeutics (TACT)
Mouse models for muscular dystrophies: an overview
Bicuspid aortic valve formation: Nos3 mutation leads to abnormal lineage patterning of neural crest cells and the second heart field
Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies
Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development
The role of enterocyte defects in the pathogenesis of congenital diarrheal disorders
Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model
Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice
Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models
Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model
Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system.
von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish