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(41 - 60 of 102)

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Immunogenicity of human embryonic stem cell-derived beta cells
Torren, C.R. van der; Zaldumbide, A.; Duinkerken, G.; Brand-Schaaf, S.H.; Peakman, M.; Stange, G.; ... ; Roep, B.O. 2017
Immunogenicity of human embryonic stem cell-derived beta cells
Article / Letter to editor
open access
Sequential intravital imaging reveals in vivo dynamics of pancreatic tissue transplanted under the kidney capsule in mice
Gurp, L. van; Loomans, C.J.M.; Krieken, P.P. van; Dharmadhikari, G.; Jansen, E.; Ringnalda, F.C.A.S.; ... ; Koning, E.J.P. de 2016
Sequential intravital imaging reveals in vivo dynamics of pancreatic tissue transplanted under the kidney capsule in mice
Article / Letter to editor
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Energy restriction and Roux-en-Y gastric bypass reduce postprandial alpha-dicarbonyl stress in obese women with type 2 diabetes
Maessen, D.E.; Hanssen, N.M.; Lips, M.A.; Scheijen, J.L.; Dijk, K.W. van; Pijl, H.; ... ; Schalkwijk, C.G. 2016
Energy restriction and Roux-en-Y gastric bypass reduce postprandial alpha-dicarbonyl stress in obese women with type 2 diabetes
Article / Letter to editor
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Conclusions/interpretation This study shows that type 2 diabetes is characterised by increased fasting and postprandial plasma alpha-dicarbonyl stress, which can be reduced by improving glucose... Show moreConclusions/interpretation This study shows that type 2 diabetes is characterised by increased fasting and postprandial plasma alpha-dicarbonyl stress, which can be reduced by improving glucose metabolism through a VLCD or RYGB. These data highlight the potential to reduce reactive alpha-dicarbonyls in obese individuals with type 2 diabetes. Trial registration: ClinicalTrials.gov NCT01167959 Show less
Investigating the lipodystrophy genetic score associations with insulin sensitivity, ectopic and visceral fat in people at risk or with diabetes: a DIRECT study
Frau, F.; Mari, A.; Thomas, E.L.; Alenaini, W.; Ruetten, H.; Hart, L. 't; ... ; DIRECT Consortium 2016
Investigating the lipodystrophy genetic score associations with insulin sensitivity, ectopic and visceral fat in people at risk or with diabetes: a DIRECT study
Article / Letter to editor
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A metabolite ratio associates with measures of insulin secretion and altered risk of type 2 diabetes; a DIRECT study
Hart, L.M. 't; Molnos, S.; Eekhoff, E.; Flogel, A.; Grallert, H.; Wahl, S.; ... ; Adamski, J. 2016
A metabolite ratio associates with measures of insulin secretion and altered risk of type 2 diabetes; a DIRECT study
Article / Letter to editor
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A common gene variant in glucokinase regulatory protein interacts with glucose metabolism on diabetic dyslipidaemia: the combined CODAM and Hoorn studies
Simons, N.; Dekker, J.M.; Greevenbroek, M.M.J. van; Nijpels, G.; Hart, L.M. 't; Kallen, C.J.H. van der; ... ; Brouwers, M.C.G. 2016
A common gene variant in glucokinase regulatory protein interacts with glucose metabolism on diabetic dyslipidaemia: the combined CODAM and Hoorn studies
Article / Letter to editor
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Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes
Ligthart, S.; Steenaard, R.V.; Peters, M.J.; Meurs, J.B.J. van; Sijbrands, E.J.G.; Uitterlinden, A.G.; ... ; BIOS Consortium 2016
Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes
Article / Letter to editor
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Simultaneous pancreas-kidney transplantation in patients with type 1 diabetes reverses elevated MBL levels in association with MBL2 genotype and VEGF expression
Bijkerk, R.; Pol, P. van der; Khairoun, M.; Gijlswijk-Jansen, D.J. van; Lievers, E.; Vries, A.P.J. de; ... ; Reinders, M.E.J. 2016
Simultaneous pancreas-kidney transplantation in patients with type 1 diabetes reverses elevated MBL levels in association with MBL2 genotype and VEGF expression
Article / Letter to editor
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Conclusions/interpretation Taken together, circulating MBL levels are associated with diabetic nephropathy and are dependent on glycaemic control, possibly in an MBL2-genotype-dependent manner.
Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy
Torren, C.R. van der; Zaldumbide, A.; Roelen, D.L.; Duinkerken, G.; Brand-Schaaf, S.H.; Peakman, M.; ... ; Roep, B.O. 2016
Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy
Article / Letter to editor
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Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice
Kooijman, S.; Wang, Y.N.; Parlevliet, E.T.; Boon, M.R.; Edelschaap, D.; Snaterse, G.; ... ; Rensen, P.C.N. 2015
Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice
Article / Letter to editor
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A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control (vol 58, pg 1855, 2015)
Yousri, N.A.; Mook-Kanamori, D.O.; Selim, M.M.D.; Takiddin, A.H.; Al-Homsi, H.; Al-Mahmoud, K.A.S.; ... ; Suhre, K. 2015
A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control (vol 58, pg 1855, 2015)
Article / Letter to editor
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Skin autofluorescence is related to tobacco smoke and nicotine exposure
Waateringe, R.P. van; Mook-Kanamori, M.J.; Slagter, S.N.; Klauw, M.M. van der; Vliet-Ostaptchouk, J.V. van; Graaff, R.; ... ; Mook-Kanamori, D.O. 2015
Skin autofluorescence is related to tobacco smoke and nicotine exposure
Article / Letter to editor
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A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control
Yousri, N.A.; Mook-Kanamori, D.O.; Selim, M.M.E.; Takiddin, A.H.; Al-Homsi, H.; Al-Mahmoud, K.A.S.; ... ; Suhre, K. 2015
A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control
Article / Letter to editor
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The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice
Beek, L. van; Klinken, J.B. van; Pronk, A.C.M.; Dam, A.D. van; Dirven, E.; Rensen, P.C.N.; ... ; Harmelen, V. van 2015
The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice
Article / Letter to editor
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Middle-aged overweight South Asian men exhibit a different metabolic adaptation to short-term energy restriction compared with Europeans
Bakker, L.E.H.; Guigas, B.; Schinkel, L.D. van; Zon, G.C.M. van der; Streefland, T.C.M.; Klinken, J.B. van; ... ; Jazet, I.M. 2015
Middle-aged overweight South Asian men exhibit a different metabolic adaptation to short-term energy restriction compared with Europeans
Article / Letter to editor
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Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up
Welsh, P.; Preiss, D.; Lloyd, S.M.; Craen, A.J. de; Jukema, J.W.; Westendorp, R.G.; ... ; Sattar, N. 2014
Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up
Article / Letter to editor
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Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss
Dharuri, H.; Hoen, P.A.C. 't; Klinken, J.B. van; Henneman, P.; Laros, J.F.J.; Lips, M.A.; ... ; Harmelen, V. van 2014
Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss
Article / Letter to editor
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Genetic associations in diabetic nephropathy: a meta-analysis (vol 54, pg 544, 2011)
Mooyaart, A.L.; Valk, E.J.J.; Es, L.A. van; Bruijn, J.A.; Heer, E. de; Freedman, B.I.; ... ; Baelde, H.J. 2014
Genetic associations in diabetic nephropathy: a meta-analysis (vol 54, pg 544, 2011)
Article / Letter to editor
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Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial
Raalte, D.H. van; Diamant, M.; Ouwens, D.M.; Ijzerman, R.G.; Linssen, M.M.L.; Guigas, B.; ... ; Serne, E.H. 2013
Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial
Article / Letter to editor
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Pleiotropic effects on lipid levels and obesity identified in multi-trait meta-analysis of genome-wide association studies (GWAS) of type 2 diabetes related traits
Lagou, V.; Magi, R.; Surakka, I.; Sarin, A.P.; Horikoshi, M.; Thorleifsson, G.; ... ; Prokopenko, I. 2013
Pleiotropic effects on lipid levels and obesity identified in multi-trait meta-analysis of genome-wide association studies (GWAS) of type 2 diabetes related traits
Article / Letter to editor
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Pages