The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles. However,... Show moreThe Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles. However, yet they have not been observed, and currently, the scientific community tries to find a signature that manifests the existence and properties of such particles. This thesis is devoted to exploring the parameter space of Feebly Interacting new physics Particles (FIPs) in a model-independent fashion using two complementary approaches. The first one is searching for FIPs at next-generation accelerator experiments called Intensity Frontier experiments. The second one is constraining the parameter space of FIPs by considering their possible impact on the observables coming from the Early Universe - Big Bang Nucleosynthesis and Cosmic Microwave Background, which are in good agreement with the predictions of the cosmological models with SM particles. They are, therefore, very sensitive to the possible existence of FIPs in the primordial plasma. As a result of the researches constituting this thesis, novel model-independent results, as well as constraints on particular models of FIPs such as Heavy Neutral Leptons, have been obtained in both of these areas. Show less
This thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single... Show moreThis thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single crystalline gold nanorods (GNRs) as our basic frameworks in the whole studies, simply because of their unique optical properties, such as the intense electromagnetic fields enhancement near the tips, and the narrow, tunable resonance with light. We first explore the lower limit of fluorescence quantum yield for single-molecule detection by enhancing the fluorescence with a single gold nanorod. Later, we develop a method to synthesize end-to-end gold nanorod dimers on glass substrates with the aid of molecular linkers, and then apply these strong plasmon coupling systems to enhance the single-molecule fluorescence under two-photon excitation. Show less
Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it... Show moreSystems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.These complex structures also make information storage and transmission in it is impossible to describe by the random variables with finite outcomes in the classical information theory. In this thesis, we use the statistical ensemble with local constraints to describe those complex systems with heterogeneous interactions and dependencies. This description also helps us find the new information-theoretical bounds in the systems with local constraints, even when the temporal dependencies among numerous units break the asymptotic equipartition property in the classical information theory.Furthermore, we find that the breaking of ensemble equivalence generally exists in systems with local constraints even without the presence of phase transition, and this ensemble nonequivalence in the systems with local constraints without phase transition can be the same strong as the one that only appears on the boundary of phase transitions caused by the long-range interactions. We also find that this breaking of ensemble equivalence will affect the limit of information storage and transmission in systems with local constraints.These results in this thesis extend our understanding of complex systems and information theory. Show less
In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson... Show moreIn this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolution. On the other hand, noise scanning tunneling microscopy is employed for measuring the shot noise which detects the charge of the carriers forming a superconducting condensate. Show less
The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information... Show moreThe elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents. Encoding information in the amplitude and/or phase of these coherent waves could lead to a drastic decrease in dissipated power, typically related to the motion of electrons ("Joule" or "Ohmic" heating).This dissertation describes the development and use of a new technique to study spin waves. This technique uses the electronic spins associated with nitrogen-vacancy (NV) centers as magnetic field sensors. An NV center is a light-emitting defect in the crystal lattice of diamond. Remarkably, the brightness of its emission depends on its spin state, sensitive to magnetic fields. This way, magnetic information can be investigated optically. Show less
This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by... Show moreThis thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”. The energy that drives inflation must be transferred to elementary particles and radiation. This process is called reheating. The unknown expansion history of the universe during the reheating era connects the cosmic microwave background (CMB) observations to inflationary physics. CMB is a relic radiation that provides us a snapshot of the primordial universe. Both the inflationary and reheating eras generate signatures to be seen via upcoming gravitational waves and CMB polarization experiments. In this thesis we show analytically a scaling behaviour that allows for an easy estimate of the reheating efficiency for one broad family of multi-field models of inflation that is called α-attractors. We show the influence of the asymmetry around the minimum of potential on the reheating efficiency. Moreover, we study the predictions for chiral gravitational waves production by a spectator gauge field sector in scalar single-field inflation. Finally, we present a new class of inflationary models that is called “shift-symmetric orbital inflation”. Show less
In unconventional high temperature superconductors, supercurrent vortices are known to spoil the Landau levels. In this thesis the emergence of Landau levels is studied in different types of... Show moreIn unconventional high temperature superconductors, supercurrent vortices are known to spoil the Landau levels. In this thesis the emergence of Landau levels is studied in different types of superconductors: Weyl superconductors, and the Fu-Kane heterostructure. It is shown that in those materials the zeroth Landau level can withstand the scattering off vortices. Show less
Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter. Many efforts are being made to develop, understand and ultimately control them, because of... Show moreSynthetic microswimmers take an important place within the interdisciplinary field of active soft matter. Many efforts are being made to develop, understand and ultimately control them, because of their great potential for fundamental studies and applications. A widely employed type is that of catalytically propelled microswimmers, such as platinum-half-coated colloids which achieve self-propulsion in aqueous hydrogen peroxide environments via a catalytic reaction taking place on the platinum. Surprisingly, although these swimmers are typically found self-propelling parallel to walls, the origins for this near-wall behavior and the influence of the walls are still largely unexplored. In this thesis, we examine the behavior of catalytic microswimmers near walls. We find that the physical property of slip of the nearby wall significantly impacts their speed. We develop a new diffusion-based analysis method, and uncover that swimmers tend to fixed heights above planar walls. Using obstacles of different shapes 3D-printed on the planar wall, we found cooperative swimmer behaviors along one-dimensional environments. Overall, our findings provide new insights into the still-debated propulsion mechanism of catalytic microswimmers, and may also aid in predicting and controlling swimmer motions in future applications, where synthetic swimmers will be needed to perform tasks inside complex environments. Show less
We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles. In short, we have characterized the diffusive... Show moreWe have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles. In short, we have characterized the diffusive properties of anisotropic dumbbell particles near surfaces. Furthermore, by using experiments and simulations, we have uncovered marked flexibility-induces effects in the Brownian motion of reconfigurable colloidal structures. Our work demonstrates the rich dynamics and possibilities for applications of shape-changing colloidal systems. We hope our findings further the study of the diffusivity of flexible objects found in complex mixtures relevant in, for example, the cosmetic, pharmaceutical and food industries, as well as in biological and drug-delivery systems. For example, our results may have implications for understanding both the diffusive behavior and the most likely conformations of macromolecular systems such as polymers, single-stranded DNA and other chain-like molecules. Show less
Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided. But flaws can also be used to... Show moreErrors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided. But flaws can also be used to design materials with unique functionalities. In the work presented here, we use two types of imperfections to create functional structures. First, we design materials that are locally stiff or soft, depending on how they are actuated, using topological imperfections: mistakes in their underlying architecture. Second, we create structures that shape-morph, because their individual elements fail, buckle, and snap- features that should be avoided otherwise. Show less
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome. This diversity is created by gene... Show moreThe human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome. This diversity is created by gene regulation, a set of mechanisms that determine, which genes are used to make proteins and which genes are kept silent. During embryonic development, gene are turned on and off in a tightly orchestrated manner, to make sure that the right cell type is created at the right time and place.In this thesis we report several studies pertaining to gene regulation in embryonic development. Each of the four chapters will cover a different layer of the gene regulation toolbox: gene inactivation by DNA methylation, transcriptional regulation in the developing kidney, regulation of protein turnover and translational regulation through micro-RNAs. Together, these studies provide a refined understanding of the crucial role of gene regulation for embryonic development. Show less
This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.The formation mechanism of these toroidal plasmas is identified and an... Show moreThis dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.The formation mechanism of these toroidal plasmas is identified and an estimate of their main plasma parameters is obtained. Furthermore, preliminary experiments are presented, aimed at heating these plasmas by absorption of microwave radiation, in order to counteract their transient nature.Through a tomographic reconstruction, cross-sectional images of the toroidal plasma are obtained, visualising the fluid flow responsible for the generation of the toroidal structure. The origin of the flow is traced back to the structure of the plasma kernel. The shocks generated by this kernel interact akin to a Mach reflection and generate a low pressure region whose replenishment transforms the plasma into a toroid. Schlieren imaging, complemented with a novel scanning-probe technique, and thermodynamic modelling, as well as deliberately breaking the flow symmetry, confirm the formation mechanism. A high-power, sub-microsecond rise time, pulsed magnetron source has been designed for the microwave heating experiments. Its detailed design and the effect of the microwave pulse on the plasma are discussed.This work is part of a larger study on self-organising knotted magnetic structures in plasma, which may find their application in nuclear fusion and astrophysical research. Show less
Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications. Along with sensing applications in biology and solid-state physics or a... Show moreSingle-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications. Along with sensing applications in biology and solid-state physics or a variety of applications in quantum information technology, molecules offer interesting possibilities for fundamental research. One of the very interesting areas is the study of charge transport and electric field sensing at the nanoscale. Developing molecular nanosensors for electric fields can not only help to fundamentally explore the motion of charges in conductors and semiconductors but can also lead to very sensitive and accurate instruments for quasi-static charge tracing or even single-electron charge detection. Such research could eventually lead to the construction of precise electric field sensors that can act as an interface between the quantum state of an electron and the outside word. We developed fluorescence molecular systems and electronic circuits with the aim of electric-field sensing and optical detection of one single electron. Show less
Geometric phases lead to a nontrivial interference result when an electron's different quantum mechanical paths choices encircle a magnetic coil in an Aharonov-Bohm experiment. They are also... Show moreGeometric phases lead to a nontrivial interference result when an electron's different quantum mechanical paths choices encircle a magnetic coil in an Aharonov-Bohm experiment. They are also responsible for the daily precession of a Foucault pendulum in Paris. A dynamical shape change induces a geometric phase, which, for instance, cats use to rotate when falling and swimmers use to swim forward.A modern application of such geometric phases has led to the notion of topological phases, which are described by a global property of the system. These phases are very different from the classical phases of matter, which are characterized by a local order parameter. A topological phase transition is therefore a fundamentally different process compared to a classical one as in a liquid-gas transition, because the former requires a change of a global topological index of the system. Topological phases can, for example, lead to the presence of traveling electronic modes which are robust against being backscattered by obstacles at the boundary of an insulator.This thesis describes some applications of geometric and topological phases in soft-matter systems. Show less