Leiden University Scholarly Publications

Crobach, M.J.T.; Duszenko, N.; Terveer, E.M.; Verduin, C.M.; Kuijper, E.J. 2018

Nucleic Acid Amplification Test Quantitation as Predictor of Toxin Presence in Clostridium difficile Infection

Article / Letter to editor

open access

Lestrade, P.P.A.; Meis, J.F.; Arends, J.P.; Beek, M.T. van der; Brauwer, E. de; Dijk, K. van; ... ; Verweij, P.E. 2016

Diagnosis and management of aspergillosis in the Netherlands: a national survey

Article / Letter to editor

metadata only

A survey of diagnosis and treatment of invasive aspergillosis was conducted in eight University Medical Centers (UMCs) and eight non-academic teaching hospitals in the Netherlands. Against a... Show moreA survey of diagnosis and treatment of invasive aspergillosis was conducted in eight University Medical Centers (UMCs) and eight non-academic teaching hospitals in the Netherlands. Against a background of emerging azole resistance in Aspergillus fumigatus routine resistance screening of clinical isolates was performed primarily in the UMCs. Azole resistance rates at the hospital level varied between 5% and 10%, although rates up to 30% were reported in high-risk wards. Voriconazole remained first choice for invasive aspergillosis in 13 out of 16 hospitals. In documented azole resistance 14 out of 16 centres treated patients with liposomal amphotericin B. Show less