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(1 - 3 of 3)
International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
Galipeau, J.; Krampera, M.; Barrett, J.; Dazzi, F.; Deans, R.J.; Debruijn, J.; ... ; Sensebe, L. 2016
International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
Article / Letter to editor
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Risk of tumorigenicity in mesenchymal stromal cell-based therapies-Bridging scientific observations and regulatory viewpoints
Barkholt, L.; Flory, E.; Jekerle, V.; Lucas-Samuel, S.; Ahnert, P.; Bisset, L.; ... ; Salmikangas, P. 2013
Risk of tumorigenicity in mesenchymal stromal cell-based therapies-Bridging scientific observations and regulatory viewpoints
Article / Letter to editor
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Defining the risks of mesenchymal stromal cell therapy
Prockop, D.J.; Brenner, M.; Fibbe, W.E.; Horwitz, E.; Blanc, K. le; Phinney, D.G.; ... ; Keating, A. 2010
Defining the risks of mesenchymal stromal cell therapy
Article / Letter to editor
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We address the issue of the potential for malignant transformation of cultured mesenchymal stromal cells (MSC) commonly used in clinical cell-therapy protocols and describe the culture conditions... Show moreWe address the issue of the potential for malignant transformation of cultured mesenchymal stromal cells (MSC) commonly used in clinical cell-therapy protocols and describe the culture conditions under which tumorigenesis is likely to be an extremely uncommon event. Show less