Leiden University Scholarly Publications

Jaarsma-Coes, M.G.; Marinkovic, M.; Astreinidou, E.; Schuurmans, M.S.; Peters, F.P.; Luyten, G.P.M.; ... ; Beenakker, J.W.M. 2020

Measuring eye deformation between planning and proton beam therapy position using magnetic resonance imaging

Article / Letter to editor

open access

Proton beam therapy (PBT) for uveal melanoma (UM) is performed in sitting position, while the acquisition of the Magnetic resonance (MR)-images for treatment planning is performed in supine... Show moreProton beam therapy (PBT) for uveal melanoma (UM) is performed in sitting position, while the acquisition of the Magnetic resonance (MR)-images for treatment planning is performed in supine position. We assessed the effect of this difference in position on the eye- and tumour- shape. Seven subjects and six UM-patients were scanned in supine and a seating mimicking position. The distances between the tumour/sclera in both positions were calculated. The median distance between both positions was 0.1 mm. Change in gravity direction produced no substantial changes in sclera and tumour shape, indicating that supinely acquired MR-images can be used to plan ocular-PBT. Show less