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(21 - 26 of 26)

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GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Rietveld, C.A.; Medland, S.E.; Derringer, J.; Yang, J.; Esko, T.; Martin, N.W.; ... ; LifeLines Cohort Study 2013
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Article / Letter to editor
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Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway
Li, G.; Diogo, D.; Wu, D.; Spoonamore, J.; Dancik, V.; Franke, L.; ... ; RACI 2013
Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway
Article / Letter to editor
metadata only
A Genome-Wide Association Study of Depressive Symptoms
Hek, K.; Demirkan, A.; Lahti, J.; Terracciano, A.; Teumer, A.; Cornelis, M.C.; ... ; Murabito, J. 2013
A Genome-Wide Association Study of Depressive Symptoms
Article / Letter to editor
metadata only
Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis
Cui, J.; Stahl, E.A.; Saevarsdottir, S.; Miceli, C.; Diogo, D.; Trynka, G.; ... ; Plenge, R.M. 2013
Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis
Article / Letter to editor
metadata only
Common variants at 12q14 and 12q24 are associated with hippocampal volume
Bis, J.C.; DeCarli, C.; Smith, A.V.; Lijn, F. van der; Crivello, F.; Fornage, M.; ... ; Cohorts Heart Aging Res Genomic Ep 2012
Common variants at 12q14 and 12q24 are associated with hippocampal volume
Article / Letter to editor
metadata only
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
Stahl, E.A.; Raychaudhuri, S.; Remmers, E.F.; Xie, G.; Eyre, S.; Thomson, B.P.; ... ; YEAR Consortium 2010
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
Article / Letter to editor
metadata only
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid arthritis (cases... Show moreTo identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid arthritis (cases) and 20,169 controls of European descent, followed by replication in an independent set of 6,768 rheumatoid arthritis cases and 8,806 controls. Of 34 SNPs selected for replication, 7 new rheumatoid arthritis risk alleles were identified at genome-wide significance (P < 5 x 10(-8)) in an analysis of all 41,282 samples. The associated SNPs are near genes of known immune function, including IL6ST, SPRED2, RBPJ, CCR6, IRF5 and PXK. We also refined associations at two established rheumatoid arthritis risk loci (IL2RA and CCL21) and confirmed the association at AFF3. These new associations bring the total number of confirmed rheumatoid arthritis risk loci to 31 among individuals of European ancestry. An additional 11 SNPs replicated at P < 0.05, many of which are validated autoimmune risk alleles, suggesting that most represent genuine rheumatoid arthritis risk alleles. Show less

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