Social anxiety is anxiety about negative evaluation and rejection by others. Social anxiety has been long related to reduced eye contact, this feature is seen as a casual and a maintaining factor... Show moreSocial anxiety is anxiety about negative evaluation and rejection by others. Social anxiety has been long related to reduced eye contact, this feature is seen as a casual and a maintaining factor of social anxiety disorder. However, related empirical findings were equivocal. The dissertation sought to address three key questions: (1) Whether social anxiety is featured by gaze avoidance. (2) Under which conditions socially anxious individuals display gaze avoidance. (3) To what extent subjective experience of gaze avoidance corresponds with actual gaze behavior. Using the combination of naturalistic social settings and wearable eye-trackers, the dissertation provides evidence for the relationship between social anxiety and gaze avoidance particularly in naturalistic social situation, and further reveals that the relationship depends on severity of social anxiety symptoms, type of social situation and age group. Besides, gaze anxiety is moderately associated with actual gaze avoidance. Altogether, the dissertation sheds light on the nature of gaze behavior adopted by socially anxious individuals in naturalistic social interactions. Show less
Although visual avoidance of faces is a hallmark feature of social anxiety disorder (SAD) on clinical and theoretical grounds, empirical support is equivocal. This review aims to clarify under... Show moreAlthough visual avoidance of faces is a hallmark feature of social anxiety disorder (SAD) on clinical and theoretical grounds, empirical support is equivocal. This review aims to clarify under which conditions socially anxious individuals display visual avoidance of faces. Through a systematic search in Web of Science and PubMed up to March 2019 we identified 61 publications that met the inclusion criteria. We discuss the influence of three factors on the extent to which socially anxious individuals avoid looking at faces: (a) severity of social anxiety symptoms (diagnosed SAD versus High Social Anxiety levels in community samples [HSA] or related characteristics [Shyness, Fear of Negative Evaluation]), (b) three types of social situation (computer facial-viewing tasks, speaking tasks, social interactions), and (c) development (age-group). Adults with SAD exhibit visual avoidance across all three types of social situations, whereas adults with HSA exhibit visual avoidance in speaking and interaction tasks but not in facial-viewing tasks. The relatively few studies with children and adolescents suggest that visual avoidance emerges during adolescence. The findings are discussed in the context of cognitive-behavioral and skills-deficit models. Suggestions for future research include the need for developmental studies and more fine-grained analyses of specific areas of the face. Show less
Traditionally, administered mass is used to describe doses of conventional chemical substances in toxicity studies. For deriving toxic doses of nanomaterials, mass and chemical composition alone... Show moreTraditionally, administered mass is used to describe doses of conventional chemical substances in toxicity studies. For deriving toxic doses of nanomaterials, mass and chemical composition alone may not adequately describe the dose, because particles with the same chemical composition can have completely different toxic mass doses depending on properties such as particle size. Other dose metrics such as particle number, volume, or surface area have been suggested, but consensus is lacking. The discussion regarding the most adequate dose metric for nanomaterials clearly needs a systematic, unbiased approach to determine the most appropriate dose metric for nanomaterials. In the present study, the authors propose such an approach and apply it to results from in vitro and in vivo experiments with silver and silica nanomaterials. The proposed approach is shown to provide a convenient tool to systematically investigate and interpret dose metrics of nanomaterials. Recommendations for study designs aimed at investigating dose metrics are provided. Show less
