Objectives: Deficiency of secreted IgM antibodies (sIgM-/-) in Ldlr-/- miceresults in accelerated atherosclerosis. However, the underlying mechanismshave not been elucidated.We aim to identify... Show moreObjectives: Deficiency of secreted IgM antibodies (sIgM-/-) in Ldlr-/- miceresults in accelerated atherosclerosis. However, the underlying mechanismshave not been elucidated.We aim to identify mechanisms by whichsecreted IgM deficiency results in increased lesion formation. Show less