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(1 - 16 of 16)
To bridge, blossom, or boost: that is the question
Arend, S.M.; Jedema, I. 2020
To bridge, blossom, or boost: that is the question
Other
open access
The Scope of Allo-HLA Cross-Reactivity By (Third Party) Virus Specific T Cells Is Surprisingly Affected By HLA Restriction Rather Than Virus Specificity
Huisman, W.; Leboux, D.A.T.; Maarel, L.E. van der; Hageman, L.; Amsen, D.; Falkenburg, J.H.F.; Jedema, I. 2018
The Scope of Allo-HLA Cross-Reactivity By (Third Party) Virus Specific T Cells Is Surprisingly Affected By HLA Restriction Rather Than Virus Specificity
Other
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Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia
Griffioen, M.; Arindrarto, W.; Borras, D.M.; Locher, I.J.; Diessen, S.A.M.E. van; Holst, R. van der; ... ; Veelken, H. 2018
Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia
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Isolation and Validation of the First Functional HLA-a*01:01 Restricted EBV-LMP2 Specific T Cells for Treatment of EBV Associated Type II/III Lymphomas
Huisman, W.; Maarel, L.E. van der; Hageman, L.; Jong, R.C.M. de; Amsen, D.; Falkenburg, J.H.F.; Jedema, I. 2018
Isolation and Validation of the First Functional HLA-a*01:01 Restricted EBV-LMP2 Specific T Cells for Treatment of EBV Associated Type II/III Lymphomas
Other
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Patient Bone Marrow Chimerism at Time of Donor Lymphocyte Infusion Predicts Development of Graft Versus Host Disease
Koster, E.A.S.; Wreede, L.C. de; Wallet-Malicka, S.; Bogers, L.; Balen, P. van; Marijt, W.; ... ; Halkes, C.J.M. 2018
Patient Bone Marrow Chimerism at Time of Donor Lymphocyte Infusion Predicts Development of Graft Versus Host Disease
Other
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Tissue damage in the skin caused by myeloablative conditioning before allogeneic stem cell transplantation results in dermal recruitment of macrophages without inflammation
Balen, P. van; Zouwen, B. van der; Kruisselbrink, A.B.; Eefting, M.; Szuhai, K.; Jordanova, E.S.; ... ; Jedema, I. 2018
Tissue damage in the skin caused by myeloablative conditioning before allogeneic stem cell transplantation results in dermal recruitment of macrophages without inflammation
Other
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A minority of tumor associated antigen specific T cells restricted to self-HLA alleles is of sufficient avidity to recognize overexpressed endogenously processed antigen
Roex, M.C.J.; Hageman, L.; Egmond, E. van; Veld, S.A.J.; Hoogstraten, C.; Germeroth, L.; ... ; Jedema, I. 2018
A minority of tumor associated antigen specific T cells restricted to self-HLA alleles is of sufficient avidity to recognize overexpressed endogenously processed antigen
Other
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Phase I/II clinical trial demonstrates feasibility, safety and effectivity of CMV-pp65-specific donor T-cells for the treatment of refractory CMV reactivation after allogeneic stem cell transplantation
Jedema, I.; Balen, P. van; Halkes, C.J.M.; Egmond, E.H.M. van; Liempt, E.A.G. van; Veld, S.A.J.; ... ; Falkenburg, J.H.F. 2018
Phase I/II clinical trial demonstrates feasibility, safety and effectivity of CMV-pp65-specific donor T-cells for the treatment of refractory CMV reactivation after allogeneic stem cell transplantation
Other
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Detailed monitoring of selective graft versus leukemia T-cell immune reactions following donor lymphocyte infusion
Bergen, C.A.M. van; Luxemburg-Heijs, S.A.P. van; Eefting, M.; Jedema, I.; Halkes, C.J.M.; Oen, M.G.; ... ; Falkenburg, J.H.F. 2011
Detailed monitoring of selective graft versus leukemia T-cell immune reactions following donor lymphocyte infusion
Other
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DELICATE BALANCE BETWEEN REGULATION AND STIMULATION AT THE ANTIGEN PRESENTING CELL SITE DETERMINES THE LIKELIHOOD OF SUCCESSFUL IN-VITRO PRIMING AND ENRICHMENT OF LEUKEMIA-REACTIVE T CELLS FROM THE NAIVE DONOR REPERTOIRE
Jedema, I.; Lam, T.S.; Meent, M. van de; Pots, J.; Hoogstraten, C.; Falkenburg, J.H.F. 2011
DELICATE BALANCE BETWEEN REGULATION AND STIMULATION AT THE ANTIGEN PRESENTING CELL SITE DETERMINES THE LIKELIHOOD OF SUCCESSFUL IN-VITRO PRIMING AND ENRICHMENT OF LEUKEMIA-REACTIVE T CELLS FROM THE NAIVE DONOR REPERTOIRE
Other
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MULTI-DIMENSIONAL RESISTANCE PHENOTYPE ALLOWS QUIESCENT LEUKEMIC STEM CELLS RESIDING AFTER TYROSINE KINASE INHIBITOR TREATMENT TO ESCAPE FROM IMMUNOLOGICAL INTERVENTIONS WITH ALLOREACTIVE T CELLS AND NK CELLS
Jedema, I.; Dreunen, L. van; Hagedoorn, R.S.; Falkenburg, J.H.F. 2011
MULTI-DIMENSIONAL RESISTANCE PHENOTYPE ALLOWS QUIESCENT LEUKEMIC STEM CELLS RESIDING AFTER TYROSINE KINASE INHIBITOR TREATMENT TO ESCAPE FROM IMMUNOLOGICAL INTERVENTIONS WITH ALLOREACTIVE T CELLS AND NK CELLS
Other
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Low Incidence of Post-Transplant EBV-Related Disease After Alemtuzumab-Mediated T Cell Depletion Is Explained by the Differential Susceptibility to Alemtuzumab of B Cells and Protective CD8 and CD4 T Cells
Halkes, C.J.M.; Jedema, I.; Wolbers, J.O.; Egmond, E.M. van; Borne, P.A. von dem; Marijt, E.W.A.F.; Falkenburg, J.H.F. 2010
Low Incidence of Post-Transplant EBV-Related Disease After Alemtuzumab-Mediated T Cell Depletion Is Explained by the Differential Susceptibility to Alemtuzumab of B Cells and Protective CD8 and CD4 T Cells
Other
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Multi-Dimensional Resistance Phenotype Allows Subpopulation of Quiescent Chronic Myeloid Leukemia Stem Cells to Universally Escape From Therapeutic Attack
Jedema, I.; Dreunen, L. van; Hagedoorn, R.S.; Falkenburg, J.H.F. 2010
Multi-Dimensional Resistance Phenotype Allows Subpopulation of Quiescent Chronic Myeloid Leukemia Stem Cells to Universally Escape From Therapeutic Attack
Other
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INDUCTION OF GVHD BY HEMATOPOIESIS-SPECIFIC T CELLS MAY OCCUR DURING AN ONGOING PROFOUND GVL REACTION DUE TO ICAM-1 MEDIATED INDUCTION OF COLLATERAL DAMAGE
Zouwen, B. van der; Kruisselbrink, A.; Borne, P. von dem; Falkenburg, J.; Jedema, I. 2010
INDUCTION OF GVHD BY HEMATOPOIESIS-SPECIFIC T CELLS MAY OCCUR DURING AN ONGOING PROFOUND GVL REACTION DUE TO ICAM-1 MEDIATED INDUCTION OF COLLATERAL DAMAGE
Other
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QUIESCENT LEUKEMIC STEM CELLS RESIDING AFTER TYROSINE KINASE INHIBITOR TREATMENT ARE NOT TARGETED BY ALLOREACTIVE T CELLS AND NK CELLS
Jedema, I.; Dreunen, L. van; Falkenburg, J. 2010
QUIESCENT LEUKEMIC STEM CELLS RESIDING AFTER TYROSINE KINASE INHIBITOR TREATMENT ARE NOT TARGETED BY ALLOREACTIVE T CELLS AND NK CELLS
Other
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Delicate balance between regulation and stimulation at the antigen presenting cell site determines the likelihood of successful priming and survival of antigen-specific T-cells from the naive donor repertoire
Jedema, I.; Lam, T.S.; Meent, M. van de; Hoogstraten, C.; Falkenburg, J.H.F. 2010
Delicate balance between regulation and stimulation at the antigen presenting cell site determines the likelihood of successful priming and survival of antigen-specific T-cells from the naive donor repertoire
Other
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