In this work, we attempt to answer the question: "How to learn robust and interpretable rule-based models from data for machine learning and data mining, and define their optimality?".Rules provide... Show moreIn this work, we attempt to answer the question: "How to learn robust and interpretable rule-based models from data for machine learning and data mining, and define their optimality?".Rules provide a simple form of storing and sharing information about the world. As humans, we use rules every day, such as the physician that diagnoses someone with flu, represented by "if a person has either a fever or sore throat (among others), then she has the flu.". Even though an individual rule can only describe simple events, several aggregated rules can represent more complex scenarios, such as the complete set of diagnostic rules employed by a physician.The use of rules spans many fields in computer science, and in this dissertation, we focus on rule-based models for machine learning and data mining. Machine learning focuses on learning the model that best predicts future (previously unseen) events from historical data. Data mining aims to find interesting patterns in the available data.To answer our question, we use the Minimum Description Length (MDL) principle, which allows us to define the statistical optimality of rule-based models. Furthermore, we empirically show that this formulation is highly competitive for real-world problems. Show less
The use of data derived from genomics and transcriptomic to further develop our understanding of Polycystic Kidney Diseases and identify novel drugs for its treatment.
