The research presented here not only describes attempts to develop selective inhibitors for SENPs and PARK7 but also provides a chemical toolbox to study the function of PARK7. Both SENPs and PARK7... Show moreThe research presented here not only describes attempts to develop selective inhibitors for SENPs and PARK7 but also provides a chemical toolbox to study the function of PARK7. Both SENPs and PARK7 are attractive therapeutic targets for drug development. The results of the research and chemical tools described in this thesis will further aid in the development of more potent and selective inhibitors of SENPs and PARK7 for therapeutic purposes. Show less
