Focuses upon social interaction patterns in the Housing Estate of Kitale (Kenya). The inhabitants of this low income Housing Estate are sensitive to the same kind of spatial characteristics of... Show moreFocuses upon social interaction patterns in the Housing Estate of Kitale (Kenya). The inhabitants of this low income Housing Estate are sensitive to the same kind of spatial characteristics of housing as are people living under similar conditions in other societies. Both their economic and housing circumstances impose a strain on daily life. The inhabitants react to these circumstances by developing patterns of expectations and behaviour vis-…-vis their neighbours which resemble those of their counterparts elsewhere, despite the cultural and economic differences between societies Show less
Intestinal schistosomiasis is a disease caused by the tre-Schistosoma mansoni (Sambon, 1907). Man is the principal final host of this parasitic worm and the intermediate host is a fresh water snail... Show moreIntestinal schistosomiasis is a disease caused by the tre-Schistosoma mansoni (Sambon, 1907). Man is the principal final host of this parasitic worm and the intermediate host is a fresh water snail. The adult worms, which are some 8-15 mm long, inhabit the portal venous system. There, the females produce large amounts of eggs, many of which are excreted with the faeces. The remaining eggs get stuck in the tissues where they die. As a result of the dead eggs bilharzial granulomas are formed which are the main cause of pathologie changes in the host. The excreted eggs hatch on immersion in water and the escaping miracidia can freely live in the water for several hours. If they succeed in penetrating an intermediate host snail (in Ethiopia; Biomphalaria pfeifferi) a mother sporocyst, several daughter sporocysts, and eventually, after some 4-5 weeks, many cercariae are produced, The phase of asexual multiplication in the snail host results in the production of large numbers of exclusively either male or female cercariae. Only snails that have been penetrated successfully by several miracidia may shed cercariae of both sexes. The free living cercariae have a short life span: most of them die within 24 hours. Man may become infected when his skin is exposed to water containing cercariae. When the cercariae penetrate man's skin they are transformed into schistosomules and in some 40-60 days these schistosomules develop into adult worms that migrate to the portal and mesenteric veins. Then eggs are produced again. Show less
This thesis describes the tropic acid enzymes which in 4 steps catalyze the metabolic pathway of the alkaloid atropine. The enzymes have been discovered in a Pseudomonas bacterium from soil... Show moreThis thesis describes the tropic acid enzymes which in 4 steps catalyze the metabolic pathway of the alkaloid atropine. The enzymes have been discovered in a Pseudomonas bacterium from soil underneath the Atropa belladonna plant, the natural producer of atropine. These 4 enzymes are highly specific and show peculiar kinetics explained by the very asymmetrical equilibrium for step 2 and a keto-enol tautomerism for the product of step 2, the 2-phenylmalonic semialdehyde. The last part concerns the regulation of enzyme synthesis by product induction and its major advantage for cell economy. This thesis was written in the Dutch Language in 1969 and at that time deposited in the Repositorium of the Library of the Technical University, Delft, The Netherlands htpps://repository.tudelft.nl/view/tno; # 268336.Only in 2019 the thesis was translated by the author in English as precise copy nearly page by page of the 1969 version (no update). The English translation is only meant to disseminate the scientific data, described in the Dutch version. It does not intend to add any new data. In case of differences in the interpretation of the intellectual property only the Dutch version counts. Show less
This study describes the development of a method for the recognition and definition of leucocyte group Four. The method can also be applied to the detection of other leucocyte groups. Essential... Show moreThis study describes the development of a method for the recognition and definition of leucocyte group Four. The method can also be applied to the detection of other leucocyte groups. Essential factors in the method were: a) the use of leucocyte agglutinins formed during pregnancy; b) an insight into the shortcomings of the agglutination test; c) the use of statistical methods to overcome these shortcomings; and d) the use of a panel consisting of the leucocytes of the women who had formed the agglutinins, and of those of their husbands. This study describes the development of a method for the recognition and definition of leucocyte group Four. The method can also be applied to the detection of other leucocyte groups. Essential factors in the method were: a) the use of leucocyte agglutinins formed during pregnancy; b) an insight into the shortcomings of the agglutination test; c) the use of statistical methods to overcome these shortcomings; and d) the use of a panel consisting of the leucocytes of the women who had formed the agglutinins, and of those of their husbands. Show less
