Leiden University Scholarly Publications

Can pharmacological conditioning as an add-on treatment optimize standard pharmacological treatment in patients with recent-onset rheumatoid arthritis?

Evaluating a shrinkage estimator for the treatment effect in clinical trials

Kaliuresis and intracellular uptake of potassium with potassium citrate and potassium chloride supplements

A Phase 1B trial in GBA1 Associated Parkinson's disease of BIA-28-6156, a glucocerebrosidase activator

A biomarker study in patients with GBA1-parkinson's disease and healthy controls

Next steps for the optimization of exon therapy for Duchenne muscular dystrophy

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

Monitoring the immune responses to vaccination and pertussis

Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients

Safety and efficacy of belimumab in patients with lupus nephritis

The Paget Trial: topical 5% imiquimod cream for noninvasive vulvar Paget disease

Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project)

How large should the next study be?

Opportunities and challenges for the development of "core outcome sets" in neuro-oncology

Endopeptidase cleavage of anti-glomerular basement membrane antibodies in vivo in severe kidney disease

Associations between depressive symptoms and disease progression in older patients with chronic kidney disease

Added value of a blinded outcome adjudication committee in an open-label randomized stroke trial

Encorafenib plus binimetinib in patients with BRAF(V)(600)-mutant non-small cell lung cancer

A randomized clinical study using optical coherence tomography to evaluate the short-term effects of high-intensity interval training on cardiac allograft vasculopathy

Development of randomized trials in adults with medulloblastoma - the example of EORTC 1634-BTG/NOA-23

Time lost due to an attack

A psychophysiological examination of the mutability of Type D personality in a therapeutic trial

Autologous bone marrow-derived mesenchymal stromal cell therapy with early tacrolimus withdrawal

A randomized single and multiple ascending dose study in healthy volunteers of LTI-291, a centrally penetrant glucocerebrosidase activator