Leiden University Scholarly Publications

Case report

Spinocerebellar ataxia type 1 characteristics in patient-derived fibroblast and iPSC-derived neuronal cultures

ETV2 upregulation marks the specification of early cardiomyocytes and endothelial cells during co-differentiation

Characterizing the secretome of licensed hiPSC-derived MSCs

Infantile fibrosarcoma with an EGFR kinase domain duplication

Elucidating mechano-pathology of osteoarthritis

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

Exploring the molecular pathogenetic basis of cutaneous lymphomas

Optimizing mutation and fusion detection in NSCLC by sequential DNA and RNA sequencing

Whole-genome analysis uncovers recurrent IKZF1 inactivation and aberrant cell adhesion in blastic plasmacytoid dendritic cell neoplasm

Molecular pathology of hereditary cerebral hemorrhage with amyloidosis-Dutch type

Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies

Splicing regulatory factors in breast cancer hallmarks and disease progression

Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals

Genomic analysis reveals recurrent deletion of JAK-STAT signaling inhibitors HNRNPK and SOCS1 in mycosis fungoides

Biological clock function is linked to proactive and reactive personality types

RNA-seq analysis of Lgr6(+) stem cells and identification of an Lgr6 isoform

Shear stress regulated signaling in renal epithelial cells and polycystic kidney disease

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Genes associated with venous thromboembolism in colorectal cancer patients

HbA(1c) is associated with altered expression in blood of cell cycle- and immune response-related genes

Non-invasive prostate cancer detection by measuring miRNA variants (isomiRs) in urine extracellular vesicles

RNA sequencing reveals a depletion of collagen targeting microRNAs in Dupuytren's disease