Leiden University Scholarly Publications

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: KLB is associated with alcohol drinking, and its gene product beta-Klotho is necessary for FGF21 regulation of alcohol preference

: Community deworming alleviates geohelminth-induced immune hyporesponsiveness

: Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data

: Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin

: Maternally supplied S-acyl-transferase is required for crystalloid organelle formation and transmission of the malaria parasite

: Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation

: Genome-wide coexpression of steroid receptors in the mouse brain: Identifying signaling pathways and functionally coordinated regions

: Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus

: Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

: Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer

: Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations

: alpha IIb beta 3 variants defined by next-generation sequencing: Predicting variants likely to cause Glanzmann thrombasthenia

: Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity

: Lack of exercise leads to significant and reversible loss of scale invariance in both aged and young mice

: The first step of peptide selection in antigen presentation by MHC class I molecules

: Reply to Albers: Acceptance of empirical evidence for gender disparities in Dutch research funding (Letter)

: Reply to Volker and Steenbeek: Multiple indicators point toward gender disparities in grant funding success in the Netherlands (Letter)

: Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue

: One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

: Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10

: Seasonal induction of GABAergic excitation in the central mammalian clock

: Transactivation of programmed ribosomal frameshifting by a viral protein

: Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation

: Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise

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