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Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma
Fc gamma RIIB regulates autoantibody responses by limiting marginal zone B cell activation
Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PL A2R1-associated membranous nephropathy
Long noncoding RNA H19X is a key mediator of TGF-beta-driven fibrosis
Cytotoxic CD4(+) T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization
Polymerase delta deficiency causes syndromic immunodeficiency with replicative stress
Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY
Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia
An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup
Inhibition of neogenin fosters resolution of inflammation and tissue regeneration
Mycobacterial growth inhibition is associated with trained innate immunity
Proteasome activity regulates CD8(+) T lymphocyte metabolism and fate specification
Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response
FOXP3(+) Tregs require WASP to restrain Th2-mediated food allergy
TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors
Therapeutic cancer vaccines
Helicobacter urease-induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma
Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease
Calcium release channel RyR2 regulates insulin release and glucose homeostasis
Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant
Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant
Targeting development of incretin-producing cells increases insulin secretion
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